We measured cohesion hysteresis between cyclopentane hydrate particles in liquid cyclopentane in the temperature range from -8 to 6 C. Cohesion hysteresis was small within scatter, and no clear temperature dependence was observed in the range studied. Too great of applied loads resulted in damage of the cyclopentane hydrate shells, causing the unconverted water core to leak out of the shell. The leaked out water then converted to irregularly shaped cyclopentane hydrate asperities on the shell after contacting the surrounding liquid cyclopentane. Cohesion hysteresis between the cyclopentane hydrate asperities was also measured and found to be similar to those between particles. The implication of these findings to the friction forces is discussed. © 2013 American Chemical Society.