Matrix-induced autologous chondrocyte implantation

David Wood; Ming Hao Zheng

doi:10.1007/978-1-59745-343-1_12

Matrix-induced autologous chondrocyte implantation

David Wood, Ming Hao Zheng

Surgery

Research output: Chapter in Book/Conference paper › Chapter › peer-review

4 Citations (Scopus)

Abstract

Matrix-induced autologous chondrocyte implantation (MACI) by means of direct inoculation of chondrocytes on a type I/IV collagen membrane for surgical implantation is less invasive and obviates periosteal harvest and suturing in most cases. It allows manufacturers to deliver a standard cell density for implantation. This chapter describes the characteristics of collagen membrane and the surgical procedures of MACI. The early clinical results based on 43 implantations in 40 patients were reported. It concluded that MACI achieves a comparable functional and histological outcomes as does conventional ACI technology.

Original language	English
Title of host publication	Cartilage Repair Strategies
Publisher	Humana Press Inc.
Pages	193-206
Number of pages	14
ISBN (Print)	1588296296, 9781588296290
DOIs	https://doi.org/10.1007/978-1-59745-343-1_12
Publication status	Published - 2007

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10.1007/978-1-59745-343-1_12

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KW - fibro cartilage

KW - Hyaline-like cartilage

KW - MACI

KW - matrix-induced autologous chondrocyte implantation

KW - type I/IV collagen membrane

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BT - Cartilage Repair Strategies

PB - Humana Press Inc.

ER -

Matrix-induced autologous chondrocyte implantation

Abstract

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