Mathematical modeling and computer simulation of needle insertion into soft tissue

Adam Wittek, George Bourantas, Benjamin Zwick, Grand Joldes, Lionel Esteban, Karol Miller

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


In this study we present a kinematic approach for modeling needle insertion into soft tissues. The kinematic approach allows the presentation of the problem as Dirichlet-type (i.e. driven by enforced motion of boundaries) and therefore weakly sensitive to unknown properties of the tissues and needle-tissue interaction. The parameters used in the kinematic approach are straightforward to determine from images. Our method uses Meshless Total Lagrangian Explicit Dynamics (MTLED) method to compute soft tissue deformations. The proposed scheme was validated against experiments of needle insertion into silicone gel samples. We also present a simulation of needle insertion into the brain demonstrating the method’s insensitivity to assumed mechanical properties of tissue.
Original languageEnglish
Article numbere0242704
Pages (from-to)1-31
JournalPLoS One
Issue number12 December
Publication statusPublished - 22 Dec 2020


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