Maternal psychiatric disorder and the risk of Autism Spectrum Disorder or intellectual disability in subsequent offspring

Jenny Fairthorne, G. Hammond, J. Bourke, Nicholas De Klerk, Helen Leonard

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

© 2015, Her Majesty the Queen in Right of Australia. Psychiatric disorders are more common in the mothers of children with autism spectrum disorder (ASD) or intellectual disability (ID) after the birth of their child. We aimed to assess the relationship between women’s psychiatric contacts and subsequent offspring with ASD/ID. We linked three Western Australian registers to investigate pre-existing maternal outpatient psychiatric contacts and the odds of ASD/ID in a subsequent child. Women with a previous outpatient psychiatric contact were more than twice as likely to have a child with ASD [OR 2.07 (95 % CI 1.7, 2.6)] or ID [OR 2.31 (2.1, 2.6)]. Further research exploring the effect on pregnancy outcomes of medications prescribed to women with psychiatric disorders is implicated.
Original languageEnglish
Pages (from-to)523-533
Number of pages12
JournalJournal of Autism and Developmental Disorders
Volume46
Issue number2
Early online date15 Sep 2015
DOIs
Publication statusPublished - 1 Feb 2016

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