Maternal eating disorders and perinatal outcomes: A three-generation study in the Norwegian mother and child cohort study

Hunna J. Watson, Stephanie Zerwas, Leila Torgersen, Kristin Gustavson, Elizabeth W. Diemer, Gun Peggy Knudsen, Ted Reichborn-Kjennerud, Cynthia M. Bulik

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Previous studies of the relationship between maternal eating disorders and adverse perinatal outcomes have failed to control for familial transmission of perinatal phenotypes, which may confound the reported association. In a unique design afforded by the Norwegian Mother and Child Cohort Study and Medical Birth Registry of Norway, we linked three generations through birth register records and maternalreported survey data to investigate whether maternal eating disorders increase risk after parsing out the contribution of familial transmission of perinatal phenotypes. The samples were 70,881 pregnancies in grandmother-mother-child triads for analyses concerning eating disorder exposure during pregnancy and 52,348 for analyses concerning lifetime maternal eating disorder exposure. As hypothesized, eating disorders predicted a higher incidence of perinatal complications even after adjusting for grandmaternal perinatal phenotypes. For example, anorexia nervosa immediately prior to pregnancy was associated with smaller birth length (relative risk = 1.62; 95% CI [1.20, 2.14]), bulimia nervosa with induced labor (relative risk = 1.21; 95% CI [1.07, 1.36]), and binge-eating disorder with several delivery complications, larger birth length (relative risk = 1.25; 95% CI [1.17, 1.34]), and large-for-gestational-age (relative risk = 1.04; 95% CI [1.01, 1.06]). Maternal pregravid body mass index and gestational weight mediated most associations. Our results support that exposure to eating disorders increases the risk for negative health outcomes in pregnant women and their babies.

Original languageEnglish
Pages (from-to)552-564
Number of pages13
JournalJournal of Abnormal Psychology
Volume126
Issue number5
DOIs
Publication statusPublished - 1 Jul 2017

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Cohort Studies
Mothers
Parturition
Phenotype
Pregnancy
Binge-Eating Disorder
Induced Labor
Birth Certificates
Bulimia Nervosa
Anorexia Nervosa
Norway
Gestational Age
Registries
Feeding and Eating Disorders
Cohort
Eating Disorders
Pregnant Women
Body Mass Index
Weights and Measures
Incidence

Cite this

Watson, Hunna J. ; Zerwas, Stephanie ; Torgersen, Leila ; Gustavson, Kristin ; Diemer, Elizabeth W. ; Knudsen, Gun Peggy ; Reichborn-Kjennerud, Ted ; Bulik, Cynthia M. / Maternal eating disorders and perinatal outcomes : A three-generation study in the Norwegian mother and child cohort study. In: Journal of Abnormal Psychology. 2017 ; Vol. 126, No. 5. pp. 552-564.
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Watson, HJ, Zerwas, S, Torgersen, L, Gustavson, K, Diemer, EW, Knudsen, GP, Reichborn-Kjennerud, T & Bulik, CM 2017, 'Maternal eating disorders and perinatal outcomes: A three-generation study in the Norwegian mother and child cohort study' Journal of Abnormal Psychology, vol. 126, no. 5, pp. 552-564. https://doi.org/10.1037/abn0000241

Maternal eating disorders and perinatal outcomes : A three-generation study in the Norwegian mother and child cohort study. / Watson, Hunna J.; Zerwas, Stephanie; Torgersen, Leila; Gustavson, Kristin; Diemer, Elizabeth W.; Knudsen, Gun Peggy; Reichborn-Kjennerud, Ted; Bulik, Cynthia M.

In: Journal of Abnormal Psychology, Vol. 126, No. 5, 01.07.2017, p. 552-564.

Research output: Contribution to journalArticle

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