Mapping the short arm of human chromosome 16

D. F. Callen, V. J. Hyland, E. G. Baker, A. Fratini, A. K. Gedeon, J. Mulley, K. E.W. Fernandez, M. H. Breuning, G. R. Sutherland

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

Physical mapping of 13 different breakpoints on the short arm of chromosome 16 using previously mapped probes and the subsequent mapping of additional probes enabled the division of this protion of the chromosome into six different intervals. D16S94 was mapped between HBA and D16S80 and is closer to PKD1 than either HBA or D16S80. A tight linkage group which includes FRA16A, D16S8, and D16S79 was identified. Seven breakpoints, including FRA16A, could not be separated by probe localizations. This study provides the basis for the development of detailed maps of the short arm of chromosome 16.

Original languageEnglish
Pages (from-to)348-354
Number of pages7
JournalGenomics
Volume4
Issue number3
DOIs
Publication statusPublished - 1 Jan 1989
Externally publishedYes

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