Management of perioperative iron deficiency anemia as part of patient blood management in France: A budget impact model-based analysis based on real world data

Sigismond Lasocki, D. Delahaye, D. Fuks, P. H. Savoie, C. Dussart, A. Hofmann, P. Paubel

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Objectives: Patient Blood Management (PBM) is defined as a patient-centered, systematic, evidence-based approach to improve patient outcomes by managing and preserving a patient's own blood, while promoting patient safety and empowerment. As a corollary, it also reduces the utilization of allogeneic blood components. However, demonstrating cost-effectiveness depends on the health insurance system considered. This analysis aims to estimate the one-year budget impact of PBM in four elective surgical areas, from French National Health Insurance and hospital perspectives. Methods: A budget impact model was developed to estimate the difference in the cost of care between scenarios with and without PBM. The impact of hematopoiesis optimization (first pillar of PBM) was studied throughout the management of preoperative anemia and iron deficiency in four types of surgeries: orthopedic, cardiac & cardiovascular, vascular & thoracic, and urologic & visceral surgery. Estimation of model's parameters was based on data collected in 10 French hospitals, literature, and on data from the French national medico-administrative database. Results: A total of 980,125 patients were modeled for all four therapeutic areas. Results shows that implementation of a PBM program could generate annual savings up to €1079 M from the French National Health Insurance perspective (€1018 M from the hospital perspective), and the sparing of 181,451 red blood cells units per year. The deterministic sensitivity analysis showed that PBM generates savings for both perspectives in most parameters tested. Conclusion: Implementing PBM programs could result in important savings for the health care system in France.

Original languageEnglish
Pages (from-to)1692-1700
Number of pages9
JournalTransfusion
Volume63
Issue number9
DOIs
Publication statusPublished - Sept 2023

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