TY - JOUR
T1 - Management of perioperative iron deficiency anemia as part of patient blood management in France
T2 - A budget impact model-based analysis based on real world data
AU - Lasocki, Sigismond
AU - Delahaye, D.
AU - Fuks, D.
AU - Savoie, P. H.
AU - Dussart, C.
AU - Hofmann, A.
AU - Paubel, P.
N1 - Funding Information:
The authors thank the investigators of the PERIOPES study, some of whose data were used for the purposes of this article. The authors would also like to thank Professor Marc Beaussier for his contribution to this work.
Publisher Copyright:
© 2023 The Authors. Transfusion published by Wiley Periodicals LLC on behalf of AABB.
PY - 2023/9
Y1 - 2023/9
N2 - Objectives: Patient Blood Management (PBM) is defined as a patient-centered, systematic, evidence-based approach to improve patient outcomes by managing and preserving a patient's own blood, while promoting patient safety and empowerment. As a corollary, it also reduces the utilization of allogeneic blood components. However, demonstrating cost-effectiveness depends on the health insurance system considered. This analysis aims to estimate the one-year budget impact of PBM in four elective surgical areas, from French National Health Insurance and hospital perspectives. Methods: A budget impact model was developed to estimate the difference in the cost of care between scenarios with and without PBM. The impact of hematopoiesis optimization (first pillar of PBM) was studied throughout the management of preoperative anemia and iron deficiency in four types of surgeries: orthopedic, cardiac & cardiovascular, vascular & thoracic, and urologic & visceral surgery. Estimation of model's parameters was based on data collected in 10 French hospitals, literature, and on data from the French national medico-administrative database. Results: A total of 980,125 patients were modeled for all four therapeutic areas. Results shows that implementation of a PBM program could generate annual savings up to €1079 M from the French National Health Insurance perspective (€1018 M from the hospital perspective), and the sparing of 181,451 red blood cells units per year. The deterministic sensitivity analysis showed that PBM generates savings for both perspectives in most parameters tested. Conclusion: Implementing PBM programs could result in important savings for the health care system in France.
AB - Objectives: Patient Blood Management (PBM) is defined as a patient-centered, systematic, evidence-based approach to improve patient outcomes by managing and preserving a patient's own blood, while promoting patient safety and empowerment. As a corollary, it also reduces the utilization of allogeneic blood components. However, demonstrating cost-effectiveness depends on the health insurance system considered. This analysis aims to estimate the one-year budget impact of PBM in four elective surgical areas, from French National Health Insurance and hospital perspectives. Methods: A budget impact model was developed to estimate the difference in the cost of care between scenarios with and without PBM. The impact of hematopoiesis optimization (first pillar of PBM) was studied throughout the management of preoperative anemia and iron deficiency in four types of surgeries: orthopedic, cardiac & cardiovascular, vascular & thoracic, and urologic & visceral surgery. Estimation of model's parameters was based on data collected in 10 French hospitals, literature, and on data from the French national medico-administrative database. Results: A total of 980,125 patients were modeled for all four therapeutic areas. Results shows that implementation of a PBM program could generate annual savings up to €1079 M from the French National Health Insurance perspective (€1018 M from the hospital perspective), and the sparing of 181,451 red blood cells units per year. The deterministic sensitivity analysis showed that PBM generates savings for both perspectives in most parameters tested. Conclusion: Implementing PBM programs could result in important savings for the health care system in France.
KW - blood transfusion
KW - budget impact model
KW - patient blood management
KW - surgery
UR - http://www.scopus.com/inward/record.url?scp=85168677414&partnerID=8YFLogxK
U2 - 10.1111/trf.17495
DO - 10.1111/trf.17495
M3 - Article
C2 - 37610057
AN - SCOPUS:85168677414
SN - 0041-1132
VL - 63
SP - 1692
EP - 1700
JO - Transfusion
JF - Transfusion
IS - 9
ER -