Management of Malignant Pleural Effusions-- What Is New

Rajesh Thomas, Bapti Roy, Fabien Maldonado, Y. C.Gary Lee

Research output: Contribution to journalArticle

Abstract

Malignant pleural effusion (MPE) is a common and challenging problem. Patients affected by MPE have a poor prognosis and suffer from breathlessness and impaired quality of life. The management of MPE has barely changed for many decades; however, recent research has driven new paradigms in the diagnosis and treatment of MPE and stimulated novel concepts that are being evaluated in many ongoing studies. This review provides an overview of recent advances in the diagnosis of MPE, including new cytopathology and imaging techniques, and the landmark studies that provide a solid evidence base to support the use of indwelling pleural catheters as first-line treatment in MPE. Lingering management dilemmas, including optimal chest drainage tube and role of surgery in MPE, and key knowledge gaps that are the focus of ongoing research are also highlighted.

Original languageEnglish
Pages (from-to)323-339
Number of pages17
JournalSeminars in Respiratory and Critical Care Medicine
Volume40
Issue number3
DOIs
Publication statusPublished - 1 Jan 2019

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