Magnetic resonance imaging-compatible circular mapping catheter: an in vivo feasibility and safety study

Delphine Elbes, Julie Magat, Assaf Govari, Yaron Ephrath, Delphine Vieillot, Christopher Beeckler, Rukshen Weerasooriya, Pierre Jais, Bruno Quesson

    Research output: Contribution to journalArticle

    5 Citations (Scopus)

    Abstract

    Aims Interventional cardiac catheter mapping is routinely guided by X-ray fluoroscopy, although radiation exposure remains a significant concern. Feasibility of catheter ablation for common flutter has recently been demonstrated under magnetic resonance imaging (MRI) guidance. The benefit of catheter ablation under MRI could be significant for complex arrhythmias such as atrial fibrillation (AF), but MRI-compatible multi-electrode catheters such as Lasso have not yet been developed. This study aimed at demonstrating the feasibility and safety of using a multi-electrode catheter [magnetic resonance (MR)-compatible Lasso] during MRI for cardiac mapping. We also aimed at measuring the level of interference between MR and electrophysiological (EP) systems.

    Methods and results Experiments were performed in vivo in sheep (N = 5) using a multi-electrode, circular, steerable, MR-compatible diagnostic catheter. The most common MRI sequences (1.5T) relevant for cardiac examination were run with the catheter positioned in the right atrium. High-quality electrograms were recorded while imaging with a maximal signal-to-noise ratio (peak-to-peak signal amplitude/peak-to-peak noise amplitude) ranging from 5.8 to 165. Importantly, MRI image quality was unchanged. Artefacts induced by MRI sequences during mapping were demonstrated to be compatible with clinical use. Phantom data demonstrated that this 10-pole circular catheter can be used safely with a maximum of 4 degrees C increase in temperature.

    Conclusions This new MR-compatible 10-pole catheter appears to be safe and effective. Combining MR and multipolar EP in a single session offers the possibility to correlate substrate information (scar, fibrosis) and EP mapping as well as online monitoring of lesion formation and electrical endpoint.

    Original languageEnglish
    Pages (from-to)458-464
    Number of pages7
    JournalEuropace
    Volume19
    Issue number3
    DOIs
    Publication statusPublished - Mar 2017

    Cite this

    Elbes, D., Magat, J., Govari, A., Ephrath, Y., Vieillot, D., Beeckler, C., ... Quesson, B. (2017). Magnetic resonance imaging-compatible circular mapping catheter: an in vivo feasibility and safety study. Europace, 19(3), 458-464. https://doi.org/10.1093/europace/euw006
    Elbes, Delphine ; Magat, Julie ; Govari, Assaf ; Ephrath, Yaron ; Vieillot, Delphine ; Beeckler, Christopher ; Weerasooriya, Rukshen ; Jais, Pierre ; Quesson, Bruno. / Magnetic resonance imaging-compatible circular mapping catheter : an in vivo feasibility and safety study. In: Europace. 2017 ; Vol. 19, No. 3. pp. 458-464.
    @article{20abf67b768d4f059466453ee4c7a234,
    title = "Magnetic resonance imaging-compatible circular mapping catheter: an in vivo feasibility and safety study",
    abstract = "Aims Interventional cardiac catheter mapping is routinely guided by X-ray fluoroscopy, although radiation exposure remains a significant concern. Feasibility of catheter ablation for common flutter has recently been demonstrated under magnetic resonance imaging (MRI) guidance. The benefit of catheter ablation under MRI could be significant for complex arrhythmias such as atrial fibrillation (AF), but MRI-compatible multi-electrode catheters such as Lasso have not yet been developed. This study aimed at demonstrating the feasibility and safety of using a multi-electrode catheter [magnetic resonance (MR)-compatible Lasso] during MRI for cardiac mapping. We also aimed at measuring the level of interference between MR and electrophysiological (EP) systems.Methods and results Experiments were performed in vivo in sheep (N = 5) using a multi-electrode, circular, steerable, MR-compatible diagnostic catheter. The most common MRI sequences (1.5T) relevant for cardiac examination were run with the catheter positioned in the right atrium. High-quality electrograms were recorded while imaging with a maximal signal-to-noise ratio (peak-to-peak signal amplitude/peak-to-peak noise amplitude) ranging from 5.8 to 165. Importantly, MRI image quality was unchanged. Artefacts induced by MRI sequences during mapping were demonstrated to be compatible with clinical use. Phantom data demonstrated that this 10-pole circular catheter can be used safely with a maximum of 4 degrees C increase in temperature.Conclusions This new MR-compatible 10-pole catheter appears to be safe and effective. Combining MR and multipolar EP in a single session offers the possibility to correlate substrate information (scar, fibrosis) and EP mapping as well as online monitoring of lesion formation and electrical endpoint.",
    keywords = "Catheter mapping electrophysiology, Magnetic resonance imaging, ABLATION, ELECTROPHYSIOLOGY, FLUOROSCOPY, GUIDANCE",
    author = "Delphine Elbes and Julie Magat and Assaf Govari and Yaron Ephrath and Delphine Vieillot and Christopher Beeckler and Rukshen Weerasooriya and Pierre Jais and Bruno Quesson",
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    Elbes, D, Magat, J, Govari, A, Ephrath, Y, Vieillot, D, Beeckler, C, Weerasooriya, R, Jais, P & Quesson, B 2017, 'Magnetic resonance imaging-compatible circular mapping catheter: an in vivo feasibility and safety study' Europace, vol. 19, no. 3, pp. 458-464. https://doi.org/10.1093/europace/euw006

    Magnetic resonance imaging-compatible circular mapping catheter : an in vivo feasibility and safety study. / Elbes, Delphine; Magat, Julie; Govari, Assaf; Ephrath, Yaron; Vieillot, Delphine; Beeckler, Christopher; Weerasooriya, Rukshen; Jais, Pierre; Quesson, Bruno.

    In: Europace, Vol. 19, No. 3, 03.2017, p. 458-464.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Magnetic resonance imaging-compatible circular mapping catheter

    T2 - an in vivo feasibility and safety study

    AU - Elbes, Delphine

    AU - Magat, Julie

    AU - Govari, Assaf

    AU - Ephrath, Yaron

    AU - Vieillot, Delphine

    AU - Beeckler, Christopher

    AU - Weerasooriya, Rukshen

    AU - Jais, Pierre

    AU - Quesson, Bruno

    PY - 2017/3

    Y1 - 2017/3

    N2 - Aims Interventional cardiac catheter mapping is routinely guided by X-ray fluoroscopy, although radiation exposure remains a significant concern. Feasibility of catheter ablation for common flutter has recently been demonstrated under magnetic resonance imaging (MRI) guidance. The benefit of catheter ablation under MRI could be significant for complex arrhythmias such as atrial fibrillation (AF), but MRI-compatible multi-electrode catheters such as Lasso have not yet been developed. This study aimed at demonstrating the feasibility and safety of using a multi-electrode catheter [magnetic resonance (MR)-compatible Lasso] during MRI for cardiac mapping. We also aimed at measuring the level of interference between MR and electrophysiological (EP) systems.Methods and results Experiments were performed in vivo in sheep (N = 5) using a multi-electrode, circular, steerable, MR-compatible diagnostic catheter. The most common MRI sequences (1.5T) relevant for cardiac examination were run with the catheter positioned in the right atrium. High-quality electrograms were recorded while imaging with a maximal signal-to-noise ratio (peak-to-peak signal amplitude/peak-to-peak noise amplitude) ranging from 5.8 to 165. Importantly, MRI image quality was unchanged. Artefacts induced by MRI sequences during mapping were demonstrated to be compatible with clinical use. Phantom data demonstrated that this 10-pole circular catheter can be used safely with a maximum of 4 degrees C increase in temperature.Conclusions This new MR-compatible 10-pole catheter appears to be safe and effective. Combining MR and multipolar EP in a single session offers the possibility to correlate substrate information (scar, fibrosis) and EP mapping as well as online monitoring of lesion formation and electrical endpoint.

    AB - Aims Interventional cardiac catheter mapping is routinely guided by X-ray fluoroscopy, although radiation exposure remains a significant concern. Feasibility of catheter ablation for common flutter has recently been demonstrated under magnetic resonance imaging (MRI) guidance. The benefit of catheter ablation under MRI could be significant for complex arrhythmias such as atrial fibrillation (AF), but MRI-compatible multi-electrode catheters such as Lasso have not yet been developed. This study aimed at demonstrating the feasibility and safety of using a multi-electrode catheter [magnetic resonance (MR)-compatible Lasso] during MRI for cardiac mapping. We also aimed at measuring the level of interference between MR and electrophysiological (EP) systems.Methods and results Experiments were performed in vivo in sheep (N = 5) using a multi-electrode, circular, steerable, MR-compatible diagnostic catheter. The most common MRI sequences (1.5T) relevant for cardiac examination were run with the catheter positioned in the right atrium. High-quality electrograms were recorded while imaging with a maximal signal-to-noise ratio (peak-to-peak signal amplitude/peak-to-peak noise amplitude) ranging from 5.8 to 165. Importantly, MRI image quality was unchanged. Artefacts induced by MRI sequences during mapping were demonstrated to be compatible with clinical use. Phantom data demonstrated that this 10-pole circular catheter can be used safely with a maximum of 4 degrees C increase in temperature.Conclusions This new MR-compatible 10-pole catheter appears to be safe and effective. Combining MR and multipolar EP in a single session offers the possibility to correlate substrate information (scar, fibrosis) and EP mapping as well as online monitoring of lesion formation and electrical endpoint.

    KW - Catheter mapping electrophysiology

    KW - Magnetic resonance imaging

    KW - ABLATION

    KW - ELECTROPHYSIOLOGY

    KW - FLUOROSCOPY

    KW - GUIDANCE

    U2 - 10.1093/europace/euw006

    DO - 10.1093/europace/euw006

    M3 - Article

    VL - 19

    SP - 458

    EP - 464

    JO - Europace

    JF - Europace

    SN - 1099-5129

    IS - 3

    ER -