Luminescence Studies of the Intracellular Distribution of a Dinuclear gold(I) N-Heterocyclic Carbene Complex

Peter Barnard; Louise Wedlock; Murray Baker; Susan Berners-Price; David Joyce; Brian Skelton; Jay Steer

doi:10.1002/anie.200601526

Luminescence Studies of the Intracellular Distribution of a Dinuclear gold(I) N-Heterocyclic Carbene Complex

Peter Barnard, Louise Wedlock, Murray Baker, Susan Berners-Price, David Joyce, Brian Skelton, Jay Steer

Research output: Contribution to journal › Article › peer-review

231 Citations (Scopus)

Abstract

Gold lights the way: A bidentate cyclophane N-heterocyclic carbene ligand has been used to synthesize a new dinuclear AuI complex of the formula [Au2L2]2+. The short Au⋅⋅⋅Au distance imposed by the rigid cyclophane ligand leads to a red-shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.

Original language	English
Pages (from-to)	6112-6116
Journal	Angewandte Chemie
Volume	45
Issue number	36
DOIs	https://doi.org/10.1002/anie.200601526
Publication status	Published - 2006

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10.1002/anie.200601526

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title = "Luminescence Studies of the Intracellular Distribution of a Dinuclear gold(I) N-Heterocyclic Carbene Complex",

abstract = "Gold lights the way: A bidentate cyclophane N-heterocyclic carbene ligand has been used to synthesize a new dinuclear AuI complex of the formula [Au2L2]2+. The short Au⋅⋅⋅Au distance imposed by the rigid cyclophane ligand leads to a red-shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.",

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year = "2006",

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AU - Barnard, Peter

AU - Wedlock, Louise

AU - Baker, Murray

AU - Berners-Price, Susan

AU - Joyce, David

AU - Skelton, Brian

AU - Steer, Jay

PY - 2006

Y1 - 2006

N2 - Gold lights the way: A bidentate cyclophane N-heterocyclic carbene ligand has been used to synthesize a new dinuclear AuI complex of the formula [Au2L2]2+. The short Au⋅⋅⋅Au distance imposed by the rigid cyclophane ligand leads to a red-shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.

AB - Gold lights the way: A bidentate cyclophane N-heterocyclic carbene ligand has been used to synthesize a new dinuclear AuI complex of the formula [Au2L2]2+. The short Au⋅⋅⋅Au distance imposed by the rigid cyclophane ligand leads to a red-shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.

U2 - 10.1002/anie.200601526

DO - 10.1002/anie.200601526

M3 - Article

SN - 1433-7851

VL - 45

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EP - 6116

JO - Angewandte Chemie

JF - Angewandte Chemie

IS - 36

ER -

Luminescence Studies of the Intracellular Distribution of a Dinuclear gold(I) N-Heterocyclic Carbene Complex

Abstract

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