Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 213-219 |
| Journal | Archives of Women's Mental Health |
| Volume | 17 |
| Issue number | 3 |
| Early online date | 25 Mar 2014 |
| DOIs | |
| Publication status | Published - 1 Jun 2014 |
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Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptoms. / Robinson, Monique; Whitehouse, Andrew; Newnham, John; Gorman, Shelley; Jacoby, Peter; Holt, B.J.; Serralha, Michael; Tearne, Jess; Holt, Patrick; Hart, Prudence; Kusel, Merci.
In: Archives of Women's Mental Health, Vol. 17, No. 3, 01.06.2014, p. 213-219.Research output: Contribution to journal › Article
TY - JOUR
T1 - Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptoms
AU - Robinson, Monique
AU - Whitehouse, Andrew
AU - Newnham, John
AU - Gorman, Shelley
AU - Jacoby, Peter
AU - Holt, B.J.
AU - Serralha, Michael
AU - Tearne, Jess
AU - Holt, Patrick
AU - Hart, Prudence
AU - Kusel, Merci
PY - 2014/6/1
Y1 - 2014/6/1
N2 - Pregnancy is a time of vulnerability for vitamin D insufficiency, and there is an emerging literature associating low levels of 25(OH)-vitamin D with depressive symptoms. However, the link between 25(OH)-vitamin D status in pregnancy and altered risk of postnatal depressive symptoms has not been examined. We hypothesise that low levels of 25(OH)-vitamin D in maternal serum during pregnancy will be associated with a higher incidence of postpartum depressive symptoms. We prospectively collected sera at 18 weeks gestation from 796 pregnant women in Perth (1989-1992) who were enrolled in the Western Australian Pregnancy Cohort (Raine) Study and measured levels of 25(OH)-vitamin D. Women reported postnatal depressive symptoms at 3 days post-delivery. Women in the lowest quartile for 25(OH)-vitamin D status were more likely to report a higher level of postnatal depression symptoms than women who were in the highest quartile for vitamin D, even after accounting for a range of confounding variables including season of birth, body mass index and sociodemographic factors. Low vitamin D during pregnancy is a risk factor for the development of postpartum depression symptoms. © 2014 Springer-Verlag.
AB - Pregnancy is a time of vulnerability for vitamin D insufficiency, and there is an emerging literature associating low levels of 25(OH)-vitamin D with depressive symptoms. However, the link between 25(OH)-vitamin D status in pregnancy and altered risk of postnatal depressive symptoms has not been examined. We hypothesise that low levels of 25(OH)-vitamin D in maternal serum during pregnancy will be associated with a higher incidence of postpartum depressive symptoms. We prospectively collected sera at 18 weeks gestation from 796 pregnant women in Perth (1989-1992) who were enrolled in the Western Australian Pregnancy Cohort (Raine) Study and measured levels of 25(OH)-vitamin D. Women reported postnatal depressive symptoms at 3 days post-delivery. Women in the lowest quartile for 25(OH)-vitamin D status were more likely to report a higher level of postnatal depression symptoms than women who were in the highest quartile for vitamin D, even after accounting for a range of confounding variables including season of birth, body mass index and sociodemographic factors. Low vitamin D during pregnancy is a risk factor for the development of postpartum depression symptoms. © 2014 Springer-Verlag.
U2 - 10.1007/s00737-014-0422-y
DO - 10.1007/s00737-014-0422-y
M3 - Article
VL - 17
SP - 213
EP - 219
JO - Archives of Women s Mental Health
JF - Archives of Women s Mental Health
SN - 1434-1816
IS - 3
ER -