Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 149-154 |
| Journal | Perspectives in Psychiatric Care |
| Volume | 50 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2014 |
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Long-term benzodiazepine use in patients with major depressive disorder in China. / Li, Y.; Xiang, Y.; Su, Y.; Shu, L.; Yu, X.; Kilbourne, A.M.; Ungvári, Gabor; Chiu, H.; Wang, G.; Bai, P.; Liu, X.; Sun, L.; Shi, J.; Chen, X.; Mei, Q.; Li, K.; Si, T.
In: Perspectives in Psychiatric Care, Vol. 50, No. 3, 2014, p. 149-154.Research output: Contribution to journal › Article
TY - JOUR
T1 - Long-term benzodiazepine use in patients with major depressive disorder in China
AU - Li, Y.
AU - Xiang, Y.
AU - Su, Y.
AU - Shu, L.
AU - Yu, X.
AU - Kilbourne, A.M.
AU - Ungvári, Gabor
AU - Chiu, H.
AU - Wang, G.
AU - Bai, P.
AU - Liu, X.
AU - Sun, L.
AU - Shi, J.
AU - Chen, X.
AU - Mei, Q.
AU - Li, K.
AU - Si, T.
PY - 2014
Y1 - 2014
N2 - Purpose: There have been no data about long-term benzodiazepine (BZD) use and its correlates in patients with major depressive disorder (MDD) in China. This study aimed to examine the prevalence of long-term BZD use (more than three months) and its demographic and clinical correlates in Chinese patients with MDD. Design and Methods: A total of 1,192 patients with MDD were examined in 10 mental health centers in China. Patients' socio-demographic and clinical characteristics and prescriptions for psychotropic drugs were recorded using a standardized form. Findings: A large portion of patients (36.2%) received long-term BZD treatment. Univariate analyses revealed that long-term BZD users were older, poorer, and had more impaired occupational functioning than patients not taking BZDs. Long-term BZD users had fewer psychotic symptoms and took less antipsychotic drugs. In multivariate analyses, long-term BZD use was independently associated with older age and more severe impaired occupational functioning; long-term BZD users were less likely to receive antipsychotic medications and traditional antidepressants (tricyclic antidepressants, tetracyclic antidepressant, and monoamine oxidase inhibitors). Practice Implications: Long-term BZD use was common in patients with MDD in China. A host of demographic and clinical factors were independently associated with long-term BZD use. © 2013 Wiley Periodicals, Inc.
AB - Purpose: There have been no data about long-term benzodiazepine (BZD) use and its correlates in patients with major depressive disorder (MDD) in China. This study aimed to examine the prevalence of long-term BZD use (more than three months) and its demographic and clinical correlates in Chinese patients with MDD. Design and Methods: A total of 1,192 patients with MDD were examined in 10 mental health centers in China. Patients' socio-demographic and clinical characteristics and prescriptions for psychotropic drugs were recorded using a standardized form. Findings: A large portion of patients (36.2%) received long-term BZD treatment. Univariate analyses revealed that long-term BZD users were older, poorer, and had more impaired occupational functioning than patients not taking BZDs. Long-term BZD users had fewer psychotic symptoms and took less antipsychotic drugs. In multivariate analyses, long-term BZD use was independently associated with older age and more severe impaired occupational functioning; long-term BZD users were less likely to receive antipsychotic medications and traditional antidepressants (tricyclic antidepressants, tetracyclic antidepressant, and monoamine oxidase inhibitors). Practice Implications: Long-term BZD use was common in patients with MDD in China. A host of demographic and clinical factors were independently associated with long-term BZD use. © 2013 Wiley Periodicals, Inc.
U2 - 10.1111/ppc.12035
DO - 10.1111/ppc.12035
M3 - Article
VL - 50
SP - 149
EP - 154
JO - Perspectives in Psychiatric Care
JF - Perspectives in Psychiatric Care
SN - 0031-5990
IS - 3
ER -