TY - JOUR
T1 - Lifetime depression history and depression risk in type 2 diabetes
T2 - A case-control study
AU - Bruce, David G
AU - Davis, Wendy A
AU - Hunter, Michael L
AU - Peters, Kirsten E
AU - Davis, Timothy M E
AU - Starkstein, Sergio E
N1 - Copyright © 2016 Elsevier Inc. All rights reserved.
PY - 2015
Y1 - 2015
N2 - AIMS: To assess whether a personal history of depression assists in risk prediction for depression in type 2 diabetes.METHODS: Age- and sex-matched participants with and without diabetes from the Busselton Health Survey were assessed for current and previous depression using the 9-item Patient Health Questionnaire and the Brief Lifetime Depression Scale (BLDS). In the diabetic participants, the temporal relationship between first depression episode and diabetes onset was also explored.RESULTS: In 184 paired participants (age 70.2±10.1years, 50% female), those with diabetes had a higher prevalence of any current depression (12.5% vs 4.3%, P<0.01) and lifetime history of major depression (30.6% vs 21.1%, P=0.06) compared to those without diabetes. After adjustment, lifetime major depression history was independently associated with any current depression in the combined sample (odds ratio (95% CI): 5.55 (3.09-9.98), P<0.001), in those with diabetes (4.17 (2.00-8.71), P<0.001), in those without diabetes (8.29 (3.24-21.23), P<0.001) and in diabetes whether sub-divided by depression first occurring before or after diabetes onset (before: 3.16 (1.38-7.24), P=0.007; after: 2.77 (1.00-7.70), P=0.051).CONCLUSIONS: Obtaining a lifetime history of major depression using the BLDS assists in depression risk prediction in type 2 diabetes regardless of whether depression preceded diabetes onset or not.
AB - AIMS: To assess whether a personal history of depression assists in risk prediction for depression in type 2 diabetes.METHODS: Age- and sex-matched participants with and without diabetes from the Busselton Health Survey were assessed for current and previous depression using the 9-item Patient Health Questionnaire and the Brief Lifetime Depression Scale (BLDS). In the diabetic participants, the temporal relationship between first depression episode and diabetes onset was also explored.RESULTS: In 184 paired participants (age 70.2±10.1years, 50% female), those with diabetes had a higher prevalence of any current depression (12.5% vs 4.3%, P<0.01) and lifetime history of major depression (30.6% vs 21.1%, P=0.06) compared to those without diabetes. After adjustment, lifetime major depression history was independently associated with any current depression in the combined sample (odds ratio (95% CI): 5.55 (3.09-9.98), P<0.001), in those with diabetes (4.17 (2.00-8.71), P<0.001), in those without diabetes (8.29 (3.24-21.23), P<0.001) and in diabetes whether sub-divided by depression first occurring before or after diabetes onset (before: 3.16 (1.38-7.24), P=0.007; after: 2.77 (1.00-7.70), P=0.051).CONCLUSIONS: Obtaining a lifetime history of major depression using the BLDS assists in depression risk prediction in type 2 diabetes regardless of whether depression preceded diabetes onset or not.
KW - Aged
KW - Aged, 80 and over
KW - Case-Control Studies
KW - Cohort Studies
KW - Cross-Sectional Studies
KW - Depression
KW - Depressive Disorder, Major
KW - Diabetes Complications
KW - Diabetes Mellitus, Type 2
KW - Diagnostic and Statistical Manual of Mental Disorders
KW - Female
KW - Health Surveys
KW - Humans
KW - Longitudinal Studies
KW - Male
KW - Middle Aged
KW - Prevalence
KW - Psychiatric Status Rating Scales
KW - Recurrence
KW - Retrospective Studies
KW - Risk Factors
KW - Western Australia
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
U2 - 10.1016/j.jdiacomp.2015.10.010
DO - 10.1016/j.jdiacomp.2015.10.010
M3 - Article
C2 - 26604164
SN - 1056-8727
VL - 30
SP - 38
EP - 42
JO - Journal of Diabetes and Its Complications
JF - Journal of Diabetes and Its Complications
IS - 1
ER -