Licensed to Kill: Mitochondria, Chloroplasts, and Cell Death

Olivier Van Aken; F. Van Breusegem

doi:10.1016/j.tplants.2015.08.002

Licensed to Kill: Mitochondria, Chloroplasts, and Cell Death

Olivier Van Aken, F. Van Breusegem

ARC Centre for Plant Energy Biology

Research output: Contribution to journal › Review article

137 Citations (Scopus)

Abstract

© 2015 Elsevier Ltd. Programmed cell death (PCD) is crucial in plant organogenesis and survival. In this review the involvement of mitochondria and chloroplasts in PCD execution is critically assessed. Recent findings support a central role for mitochondria in PCD, with newly identified components of the mitochondrial electron transport chain (mETC), FOF1 ATP synthase, cardiolipins, and ATPase AtOM66. While chloroplasts received less attention, their contribution to PCD is well supported, suggesting that they possibly contribute by producing reactive oxygen species (ROS) in the presence of light or even contribute through cytochrome f release. Finally we discuss two working models where mitochondria and chloroplasts could cooperatively execute PCD: mitochondria initiate the commitment steps and recruit chloroplasts for swift execution or, alternatively, mitochondria and chloroplasts could operate in parallel.

Original language	English
Pages (from-to)	754-766
Number of pages	13
Journal	Trends in Plant Science
Volume	20
Issue number	11
Early online date	3 Oct 2015
DOIs	https://doi.org/10.1016/j.tplants.2015.08.002
Publication status	Published - Nov 2015

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10.1016/j.tplants.2015.08.002

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@article{93d4b442330e4e6bbccbd5e8d9e81774,

title = "Licensed to Kill: Mitochondria, Chloroplasts, and Cell Death",

abstract = "{\textcopyright} 2015 Elsevier Ltd. Programmed cell death (PCD) is crucial in plant organogenesis and survival. In this review the involvement of mitochondria and chloroplasts in PCD execution is critically assessed. Recent findings support a central role for mitochondria in PCD, with newly identified components of the mitochondrial electron transport chain (mETC), FOF1 ATP synthase, cardiolipins, and ATPase AtOM66. While chloroplasts received less attention, their contribution to PCD is well supported, suggesting that they possibly contribute by producing reactive oxygen species (ROS) in the presence of light or even contribute through cytochrome f release. Finally we discuss two working models where mitochondria and chloroplasts could cooperatively execute PCD: mitochondria initiate the commitment steps and recruit chloroplasts for swift execution or, alternatively, mitochondria and chloroplasts could operate in parallel.",

author = "{Van Aken}, Olivier and {Van Breusegem}, F.",

year = "2015",

month = nov,

doi = "10.1016/j.tplants.2015.08.002",

language = "English",

volume = "20",

pages = "754--766",

journal = "Trends in Plant Science",

issn = "1360-1385",

publisher = "Elsevier",

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TY - JOUR

T1 - Licensed to Kill: Mitochondria, Chloroplasts, and Cell Death

AU - Van Aken, Olivier

AU - Van Breusegem, F.

PY - 2015/11

Y1 - 2015/11

N2 - © 2015 Elsevier Ltd. Programmed cell death (PCD) is crucial in plant organogenesis and survival. In this review the involvement of mitochondria and chloroplasts in PCD execution is critically assessed. Recent findings support a central role for mitochondria in PCD, with newly identified components of the mitochondrial electron transport chain (mETC), FOF1 ATP synthase, cardiolipins, and ATPase AtOM66. While chloroplasts received less attention, their contribution to PCD is well supported, suggesting that they possibly contribute by producing reactive oxygen species (ROS) in the presence of light or even contribute through cytochrome f release. Finally we discuss two working models where mitochondria and chloroplasts could cooperatively execute PCD: mitochondria initiate the commitment steps and recruit chloroplasts for swift execution or, alternatively, mitochondria and chloroplasts could operate in parallel.

AB - © 2015 Elsevier Ltd. Programmed cell death (PCD) is crucial in plant organogenesis and survival. In this review the involvement of mitochondria and chloroplasts in PCD execution is critically assessed. Recent findings support a central role for mitochondria in PCD, with newly identified components of the mitochondrial electron transport chain (mETC), FOF1 ATP synthase, cardiolipins, and ATPase AtOM66. While chloroplasts received less attention, their contribution to PCD is well supported, suggesting that they possibly contribute by producing reactive oxygen species (ROS) in the presence of light or even contribute through cytochrome f release. Finally we discuss two working models where mitochondria and chloroplasts could cooperatively execute PCD: mitochondria initiate the commitment steps and recruit chloroplasts for swift execution or, alternatively, mitochondria and chloroplasts could operate in parallel.

U2 - 10.1016/j.tplants.2015.08.002

DO - 10.1016/j.tplants.2015.08.002

M3 - Review article

C2 - 26442680

SN - 1360-1385

VL - 20

SP - 754

EP - 766

JO - Trends in Plant Science

JF - Trends in Plant Science

IS - 11

ER -

Licensed to Kill: Mitochondria, Chloroplasts, and Cell Death

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