Les ARN de transfert une nouvelle source de petits ARN non-codants chez Arabidopsis thaliana

Geoffrey Eugene Andre Morelle

Les ARN de transfert une nouvelle source de petits ARN non-codants chez Arabidopsis thaliana

Translated title of the contribution: Transfer RNAs are a new source of small non-coding RNAs in Arabidopsis thaliana

Geoffrey Eugene Andre Morelle

School of Molecular Sciences

Research output: Thesis › Doctoral Thesis

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Abstract

Recently a class of small RNAs (tRNA derived RNA fragments :tRFs) has emerged. In plants, despite that the existence of RFs has been reported, only few data are available. Three questions have been addressed. What enzyme is responsible or tRF biogenesis, where are tRFs generated and are tRFs only degradation by-products? Using various experiments we confirmed the existence of tAFs in plants, we also identified endonucleases that were good candidates for tRNA cleavage. Further experiments ted us to abetter understanding of tRFs function and biogenesis.

Translated title of the contribution	Transfer RNAs are a new source of small non-coding RNAs in Arabidopsis thaliana
Original language	French
Qualification	Doctor of Philosophy
Awarding Institution	The University of Western Australia
Award date	23 Jan 2017
Publication status	Unpublished - 2015

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THESIS - DOCTOR OF PHILOSOPHY - MORELLE Geoffrey Eugene Andre - 2015
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title = "Les ARN de transfert une nouvelle source de petits ARN non-codants chez Arabidopsis thaliana",

abstract = "Recently a class of small RNAs (tRNA derived RNA fragments :tRFs) has emerged. In plants, despite that the existence of RFs has been reported, only few data are available. Three questions have been addressed. What enzyme is responsible or tRF biogenesis, where are tRFs generated and are tRFs only degradation by-products? Using various experiments we confirmed the existence of tAFs in plants, we also identified endonucleases that were good candidates for tRNA cleavage. Further experiments ted us to abetter understanding of tRFs function and biogenesis. ",

keywords = "Arabidopsis, Transfer RNA, tRNA, Endonuclease, RNA turnover, RNA cleavage",

author = "Morelle, \{Geoffrey Eugene Andre\}",

year = "2015",

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school = "The University of Western Australia",

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TY - BOOK

T1 - Les ARN de transfert une nouvelle source de petits ARN non-codants chez Arabidopsis thaliana

AU - Morelle, Geoffrey Eugene Andre

PY - 2015

Y1 - 2015

N2 - Recently a class of small RNAs (tRNA derived RNA fragments :tRFs) has emerged. In plants, despite that the existence of RFs has been reported, only few data are available. Three questions have been addressed. What enzyme is responsible or tRF biogenesis, where are tRFs generated and are tRFs only degradation by-products? Using various experiments we confirmed the existence of tAFs in plants, we also identified endonucleases that were good candidates for tRNA cleavage. Further experiments ted us to abetter understanding of tRFs function and biogenesis.

AB - Recently a class of small RNAs (tRNA derived RNA fragments :tRFs) has emerged. In plants, despite that the existence of RFs has been reported, only few data are available. Three questions have been addressed. What enzyme is responsible or tRF biogenesis, where are tRFs generated and are tRFs only degradation by-products? Using various experiments we confirmed the existence of tAFs in plants, we also identified endonucleases that were good candidates for tRNA cleavage. Further experiments ted us to abetter understanding of tRFs function and biogenesis.

KW - Arabidopsis

KW - Transfer RNA

KW - tRNA

KW - Endonuclease

KW - RNA turnover

KW - RNA cleavage

M3 - Doctoral Thesis

ER -

Les ARN de transfert une nouvelle source de petits ARN non-codants chez Arabidopsis thaliana

Abstract

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