Lage incidentie van non-Hodgkin-lymfoom, maar hoge seroprevalentie van HTLV-I op Curaçao

A. Ester, J C Nossent, C M Coronel

Research output: Contribution to journalArticlepeer-review


OBJECTIVE: To determine whether the low incidence of non-Hodgkin's lymphoma (NHL) in Curaçao has changed in comparison with the increase in incidence in many western countries, and to investigate the role of the HTLV-I infection that is endemic in the Caribbean area.

DESIGN: Retrospective.

SETTING: Curaçao, Netherlands Antilles.

METHOD: Retrospective file analysis in the only hospital in Curaçao.

RESULTS: During the period 1987-1992, 31 patients had a histologically confirmed diagnosis of NHL resulting in an annual incidence rate of 4.9/100,000 adults. There was a strong age-related increase in NHL incidence rate (0.5 for patients < 30 years to 17.8 for patients > or = 70 years), with a male to female ratio of I. (In the western world the incidence is 12-14, in the seventies it was 4.5 in Curaçao.) Seven of 12 patients (58%) tested were seropositive for HTLV-I. Median survival was 6 months, despite conventional therapy.

CONCLUSION: While HTLV-I infection can often be demonstrated in NHL patients in Curaçao, NHL incidence has remained low over the past 25 years.

Original languageDutch
Pages (from-to)1119-1122
Number of pages4
JournalNederlands Tijdschrift voor Geneeskunde
Issue number21
Publication statusPublished - 25 May 1996
Externally publishedYes

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