Abstract
Suction lesions of the brachium of the left superior colliculus (SC) and pretectal region were made in 6-11-day-old hooded rats. Central retinal projections were examined 15-261 days later by injecting the right eye of each rat with horseradish peroxidase. Retinal fibres were found to have regrown either within glial and connective tissue membranes which formed over the lesion cavity or across the surface of the lesion itself. The axons sometimes grew up the rostral face of the remaining SC to reach the superficial tectal layers; however, there was no significant penetration into the SC neuropil.
| Original language | English |
|---|---|
| Pages (from-to) | 10-16 |
| Number of pages | 7 |
| Journal | Neuroscience Letters |
| Volume | 70 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 25 Sep 1986 |
| Externally published | Yes |
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Lack of ingrowth of retinal axons into the visually deafferented superior colliculus in young rats : a horseradish peroxidase study. / Gan, S. K.; Harvey, A. R.
In: Neuroscience Letters, Vol. 70, No. 1, 25.09.1986, p. 10-16.Research output: Contribution to journal › Article
TY - JOUR
T1 - Lack of ingrowth of retinal axons into the visually deafferented superior colliculus in young rats
T2 - a horseradish peroxidase study
AU - Gan, S. K.
AU - Harvey, A. R.
PY - 1986/9/25
Y1 - 1986/9/25
N2 - Suction lesions of the brachium of the left superior colliculus (SC) and pretectal region were made in 6-11-day-old hooded rats. Central retinal projections were examined 15-261 days later by injecting the right eye of each rat with horseradish peroxidase. Retinal fibres were found to have regrown either within glial and connective tissue membranes which formed over the lesion cavity or across the surface of the lesion itself. The axons sometimes grew up the rostral face of the remaining SC to reach the superficial tectal layers; however, there was no significant penetration into the SC neuropil.
AB - Suction lesions of the brachium of the left superior colliculus (SC) and pretectal region were made in 6-11-day-old hooded rats. Central retinal projections were examined 15-261 days later by injecting the right eye of each rat with horseradish peroxidase. Retinal fibres were found to have regrown either within glial and connective tissue membranes which formed over the lesion cavity or across the surface of the lesion itself. The axons sometimes grew up the rostral face of the remaining SC to reach the superficial tectal layers; however, there was no significant penetration into the SC neuropil.
KW - Denervation
KW - Lesion
KW - Rat
KW - Regeneration
KW - Retinal axon
KW - Superior colliculus
KW - Visual system
UR - http://www.scopus.com/inward/record.url?scp=0022495902&partnerID=8YFLogxK
U2 - 10.1016/0304-3940(86)90429-5
DO - 10.1016/0304-3940(86)90429-5
M3 - Article
VL - 70
SP - 10
EP - 16
JO - Neuroscience Letter
JF - Neuroscience Letter
SN - 0304-3940
IS - 1
ER -