Lack of efficacy of single dose prednisolone in moderately severe asthma

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    Abstract

    Objective: To assess the effectiveness of single-dose prednisolone in reducing the length of illness and hospital stay in children admitted with moderately severe asthma.Design: A randomised, double-blind, controlled trial of a single dose of prednisolone in 64 children presenting with an acute attack of asthma with arterial oxygen saturation less than 93%.Results: No significant differences in the rate of recovery of oxygen saturation, lung function measurements or duration of hospital stay were found.Conclusions: This study failed to confirm the benefit of a single dose of prednisolone in the management of children with acute severe asthma.
    Original languageEnglish
    Pages (from-to)701-704
    JournalMedical Journal of Australia
    Volume160
    Publication statusPublished - 1994

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