TY - JOUR
T1 - Laboratory-based surveillance of Clostridium difficile strains circulating in the Australian healthcare setting in 2012
AU - Collins, Deirdre A.
AU - Putsathit, Papanin
AU - Elliott, Briony
AU - Riley, Thomas V.
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Clostridium difficile infection (CDI) has risen in prominence in Australia recently. We conducted laboratory-based surveillance of CDI to examine C. difficile circulating in Australia in October/November 2012. We collected 542 isolates from all States and Territories of Australia except the Northern Territory. The most common ribotypes (RTs) were RTs 014/020 (25.5%), 002 (10.5%), 056 (5.9%) and 070 (4.2%). The survey results were compared with results from a similar Australian survey conducted in 2010. Proportions of RTs 014/020 and 002 remained similar, while RTs 056 (5.9%), 015 (4.1%), 017 (3.3%) and 244 (2.4%) increased in prevalence. Basic clinical and demographic data were available for 338 cases. The majority were healthcare facility-associated (HCFA-CDI, 51.5%) while 17.5% were community-associated (CA-CDI). While no RTs were associated with CA-CDI, RTs 056 and 126 were recently found in Australian production animals, indicating a possible community health threat in Australia.
AB - Clostridium difficile infection (CDI) has risen in prominence in Australia recently. We conducted laboratory-based surveillance of CDI to examine C. difficile circulating in Australia in October/November 2012. We collected 542 isolates from all States and Territories of Australia except the Northern Territory. The most common ribotypes (RTs) were RTs 014/020 (25.5%), 002 (10.5%), 056 (5.9%) and 070 (4.2%). The survey results were compared with results from a similar Australian survey conducted in 2010. Proportions of RTs 014/020 and 002 remained similar, while RTs 056 (5.9%), 015 (4.1%), 017 (3.3%) and 244 (2.4%) increased in prevalence. Basic clinical and demographic data were available for 338 cases. The majority were healthcare facility-associated (HCFA-CDI, 51.5%) while 17.5% were community-associated (CA-CDI). While no RTs were associated with CA-CDI, RTs 056 and 126 were recently found in Australian production animals, indicating a possible community health threat in Australia.
KW - Australia
KW - CDI
KW - Clostridium difficile
KW - molecular epidemiology
KW - ribotyping
UR - http://www.scopus.com/inward/record.url?scp=85013465410&partnerID=8YFLogxK
U2 - 10.1016/j.pathol.2016.10.013
DO - 10.1016/j.pathol.2016.10.013
M3 - Article
C2 - 28237369
AN - SCOPUS:85013465410
VL - 49
SP - 309
EP - 313
JO - Pathology
JF - Pathology
SN - 0031-3025
IS - 3
ER -