Keratoprosthesis results in animals: An update

Background: The report presented is an update on continuing development work on modified PHEMA core-and-shirt KPros in animals.Methods: Two variations (improved wet-eye, and dry-eye) of a prototype core-and-skirt Chirila KPro are described. The clinical success rate on implantation of these versions of the Chirila KPro was assessed.Results: It was found that a significant improvement in retention rate was shown in the improved model but. that the dry-eye model failed early in two of the three implanted.Conclusions: The significance of the improved strength and the reasons for disappointing results with the early dry-eye KPros are discussed. Ongoing work is briefly outlined.