Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Neva C. Durand, James T. Robinson, Muhammad S. Shamim, Ido Machol, Jill P. Mesirov, Eric S. Lander, Erez Lieberman Aiden

Research output: Contribution to journalArticlepeer-review

353 Citations (Scopus)

Abstract

Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.

Original languageEnglish
Pages (from-to)99-101
Number of pages3
JournalCell Systems
Volume3
Issue number1
DOIs
Publication statusPublished - 27 Jul 2016

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