Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Neva C. Durand; James T. Robinson; Muhammad S. Shamim; Ido Machol; Jill P. Mesirov; Eric S. Lander; Erez Lieberman Aiden

doi:10.1016/j.cels.2015.07.012

Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Neva C. Durand, James T. Robinson, Muhammad S. Shamim, Ido Machol, Jill P. Mesirov, Eric S. Lander, Erez Lieberman Aiden

UWA School of Agriculture and Environment

Research output: Contribution to journal › Article › peer-review

1101 Citations (Scopus)

Abstract

Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.

Original language	English
Pages (from-to)	99-101
Number of pages	3
Journal	Cell Systems
Volume	3
Issue number	1
DOIs	https://doi.org/10.1016/j.cels.2015.07.012
Publication status	Published - 27 Jul 2016

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10.1016/j.cels.2015.07.012Licence: CC BY

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abstract = "Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.",

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AU - Lander, Eric S.

AU - Aiden, Erez Lieberman

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AB - Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.

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Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Abstract

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