Jones matrix-based speckle-decorrelation angiography using polarization-sensitive optical coherence tomography

Peijun Gong, Qingyun Li, Qiang Wang, Karol Karnowski, David D. Sampson

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We show that polarization-sensitive optical coherence tomography angiography (PS-OCTA) based on full Jones matrix assessment of speckle decorrelation offers improved contrast and depth of vessel imaging over conventional OCTA. We determine how best to combine the individual Jones matrix elements and compare the resulting image quality to that of a conventional OCT scanner by co-locating and imaging the same skin locations with closely matched scanning setups. Vessel projection images from finger and forearm skin demonstrate the benefits of Jones matrix-based PS-OCTA. Our study provides a promising starting point and a useful reference for future pre-clinical and clinical applications of Jones matrix-based PS-OCTA.

Original languageEnglish
Article numbere202000007
JournalJournal of Biophotonics
Volume13
Issue number9
DOIs
Publication statusPublished - 1 Sep 2020

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