Isolation and identification of bioactive compounds from Eremophila glabra and Biserrula pelecinus

Azizah Algreiby

Research output: ThesisDoctoral Thesis

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Abstract

This thesis presents the isolation and identification of natural compounds from Eremophila glabra and Biserrula pelecinus for their antibacterial and antimethanogenic activity. These two plants were shown previously to have antimethanogenic and antibacterial activity. However, the main bioactive compounds responsible for their biological activity were unknown. In this thesis, isolation of the bioactive compounds was achieved using bioassay-guided fractionation. The structures of the active compounds were elucidated using mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopic techniques. A number of bioactive compounds were isolated from Eremophila glabra and Biserrula pelecinus, where some of these compounds are described for the first time, and their activity was confirmed using relevant bioassays.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Award date16 Nov 2018
DOIs
Publication statusUnpublished - 2018

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