TY - JOUR
T1 - Isolates of cytomegalovirus (CMV) from the black rat Rattus rattus form a distinct group of rat CMV
AU - Smith, Lee
AU - Tonkin, Joanne
AU - Lawson, Malcolm
AU - Shellam, Geoffrey
PY - 2004
Y1 - 2004
N2 - Two different betaherpesviruses, the English and Maastricht species of rat cytomegalovirus (CMV), have previously been isolated from Rattus norvegicus. CMVs were isolated from both the brown rat, R. norvegicus, and the black rat, R. rattus, within Australia. The viruses isolated from R. norvegicus appeared to be genetically related to the English species of rat CMV by PCR, RFLP, and sequencing, but the viruses isolated from R. rattus were distinct from both prototype virus species, although more closely genetically related to the Maastricht virus. This is the first genetic characterization of cytomegaloviruses from R. rattus, and the first isolation of CMVs from Australian rats.
AB - Two different betaherpesviruses, the English and Maastricht species of rat cytomegalovirus (CMV), have previously been isolated from Rattus norvegicus. CMVs were isolated from both the brown rat, R. norvegicus, and the black rat, R. rattus, within Australia. The viruses isolated from R. norvegicus appeared to be genetically related to the English species of rat CMV by PCR, RFLP, and sequencing, but the viruses isolated from R. rattus were distinct from both prototype virus species, although more closely genetically related to the Maastricht virus. This is the first genetic characterization of cytomegaloviruses from R. rattus, and the first isolation of CMVs from Australian rats.
U2 - 10.1099/vir.0.79839-0
DO - 10.1099/vir.0.79839-0
M3 - Article
SN - 0022-1317
VL - 85
SP - 1313
EP - 1317
JO - Journal of General Virology
JF - Journal of General Virology
IS - 5
ER -