TY - JOUR
T1 - Is the earlier age at onset of schizophrenia in males a confounded finding
AU - Jablensky, Assen
AU - Cole, S.W.
PY - 1997
Y1 - 1997
N2 - Background The finding of an earlier age at onset of schizophrenia in males compared with females, replicated across a number of studies, appears to be so robust as to support hypotheses about gender differences in the aetiology of the disorder. However, the possibility that this observed gender effect might reflect other confounding variables has not been adequately explored.Method We analysed data on 778 men and 653 women, in three developing countries and in seven developed countries, who had been assessed in the WHO 10-country study of schizophrenia. We applied a generalised linear modelling strategy to estimate the unconfounded contributions of gender, family history, premorbid personality and marital status to age at onset.Results The model that explained the highest percentage of the total variance indicated strong main effects (P
AB - Background The finding of an earlier age at onset of schizophrenia in males compared with females, replicated across a number of studies, appears to be so robust as to support hypotheses about gender differences in the aetiology of the disorder. However, the possibility that this observed gender effect might reflect other confounding variables has not been adequately explored.Method We analysed data on 778 men and 653 women, in three developing countries and in seven developed countries, who had been assessed in the WHO 10-country study of schizophrenia. We applied a generalised linear modelling strategy to estimate the unconfounded contributions of gender, family history, premorbid personality and marital status to age at onset.Results The model that explained the highest percentage of the total variance indicated strong main effects (P
U2 - 10.1192/bjp.170.3.234
DO - 10.1192/bjp.170.3.234
M3 - Article
VL - 170
SP - 234
EP - 240
JO - British Journal of Psychiatry
JF - British Journal of Psychiatry
ER -