Is asthma control more than just an absence of symptoms? An expert consensus statement

Giorgio Walter Canonica, Antonio Spanevello, Luis Pérez de Llano, Christian Domingo Ribas, John D Blakey, Gabriel Garcia, Hiromasa Inoue, Margareth Dalcolmo, Dong Yang, Soniya Mokashi, Abhishek Kurne, Aman Kapil Butta

Research output: Contribution to journalArticlepeer-review


PURPOSE: Definitions and measures of asthma control used in clinical trials and in clinical practice vary considerably. There is also misalignment between patients and healthcare professionals (HCPs) in terms of understanding and managing asthma control. This study aimed to progress towards a consensus definition of asthma control, and evaluate disparities between HCP and patient perspectives. BASIC PROCEDURES: A two-stage Delphi questionnaire involving asthma specialists sought to identify areas of consensus on aspects of asthma control in clinical practice. Results were compared with those of a structured literature review to assess if existing guidance and measures of asthma control used in studies correlated with practice. Eighty-two panelists took part in the Delphi questionnaire. The structured literature review included 185 manuscripts and 31 abstracts. MAIN FINDINGS: Panelists agreed that there was no standard definition of asthma control, confirmed by a total of 19 different composite consensus/guideline definitions and/or validated measures of control being identified across the Delphi study and literature review. Panelists agreed on the positive associations of well-controlled asthma with patient outcomes, but not on the components or thresholds of a working definition of control. PRINCIPAL CONCLUSIONS: A universally accepted definition and measure of asthma control that is utilized and understood by patients, HCPs, and researchers is required.
Original languageEnglish
Article number106942
JournalRespiratory Medicine
Publication statusPublished - Oct 2022
Externally publishedYes


Dive into the research topics of 'Is asthma control more than just an absence of symptoms? An expert consensus statement'. Together they form a unique fingerprint.

Cite this