Iron overload diseases: the chemical speciation of non-heme iron deposits in iron loaded mammalian tissues

Tim St Pierre; W. Chua-Anusorn; J. Webb; D.J. Macey

doi:10.1023/A:1012636510472

Iron overload diseases: the chemical speciation of non-heme iron deposits in iron loaded mammalian tissues

Tim St Pierre, W. Chua-Anusorn, J. Webb, D.J. Macey

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Fe-57 Mossbauer spectra of iron overloaded human spleen, rat spleen and rat liver tissue samples at 78 K were found to consist of a quadrupole doublet (major component) with magnetic sextet (minor component with fractional spectral area F-s). The distributions of F-s for spleen tissue from two different clinically identifiable groups (n=7 and n=12) of thalassemic patients were found to be significantly different. The value of F-s for dietary-iron loaded rat liver was found to rise significantly with age/duration (up to 24 months) of iron loading.

Original language	English
Pages (from-to)	75-81
Journal	Hyperfine Interactions
Volume	126
DOIs	https://doi.org/10.1023/A:1012636510472
Publication status	Published - 2000

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title = "Iron overload diseases: the chemical speciation of non-heme iron deposits in iron loaded mammalian tissues",

abstract = "Fe-57 Mossbauer spectra of iron overloaded human spleen, rat spleen and rat liver tissue samples at 78 K were found to consist of a quadrupole doublet (major component) with magnetic sextet (minor component with fractional spectral area F-s). The distributions of F-s for spleen tissue from two different clinically identifiable groups (n=7 and n=12) of thalassemic patients were found to be significantly different. The value of F-s for dietary-iron loaded rat liver was found to rise significantly with age/duration (up to 24 months) of iron loading.",

author = "{St Pierre}, Tim and W. Chua-Anusorn and J. Webb and D.J. Macey",

year = "2000",

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pages = "75--81",

journal = "Hyperfine Interactions",

issn = "0304-3843",

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T1 - Iron overload diseases: the chemical speciation of non-heme iron deposits in iron loaded mammalian tissues

AU - St Pierre, Tim

AU - Chua-Anusorn, W.

AU - Webb, J.

AU - Macey, D.J.

PY - 2000

Y1 - 2000

N2 - Fe-57 Mossbauer spectra of iron overloaded human spleen, rat spleen and rat liver tissue samples at 78 K were found to consist of a quadrupole doublet (major component) with magnetic sextet (minor component with fractional spectral area F-s). The distributions of F-s for spleen tissue from two different clinically identifiable groups (n=7 and n=12) of thalassemic patients were found to be significantly different. The value of F-s for dietary-iron loaded rat liver was found to rise significantly with age/duration (up to 24 months) of iron loading.

AB - Fe-57 Mossbauer spectra of iron overloaded human spleen, rat spleen and rat liver tissue samples at 78 K were found to consist of a quadrupole doublet (major component) with magnetic sextet (minor component with fractional spectral area F-s). The distributions of F-s for spleen tissue from two different clinically identifiable groups (n=7 and n=12) of thalassemic patients were found to be significantly different. The value of F-s for dietary-iron loaded rat liver was found to rise significantly with age/duration (up to 24 months) of iron loading.

U2 - 10.1023/A:1012636510472

DO - 10.1023/A:1012636510472

M3 - Article

VL - 126

SP - 75

EP - 81

JO - Hyperfine Interactions

JF - Hyperfine Interactions

SN - 0304-3843

ER -

Iron overload diseases: the chemical speciation of non-heme iron deposits in iron loaded mammalian tissues

Abstract

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