Burn injury impacts physical function and quality of life in burns survivors beyond the initial injury. Deterioration in physical function post-burn injury becomes more apparent from approximately 45-50 years of age. This thesis investigated the relationship between neuroplasticity (ability of the brain to change structurally and functionally), burn injury in older adults and rehabilitation outcomes. This thesis showed that non-injured older adults demonstrated a delayed repetitive transcranial magnetic stimulation (rTMS) induced neuroplastic response, whereas older adults with a minor burn injury demonstrated no rTMS-induced neuroplastic response at six weeks post-injury. Capacity for neuroplastic response may translate to better functional outcomes.