Investigating neuroplasticity in burn injury in older adults

Casey John Whife

doi:10.26182/5bee643a233ba

Investigating neuroplasticity in burn injury in older adults

Casey John Whife

UWA Medical School

Research output: Thesis › Master's Thesis

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Abstract

Burn injury impacts physical function and quality of life in burns survivors beyond the initial injury. Deterioration in physical function post-burn injury becomes more apparent from approximately 45-50 years of age. This thesis investigated the relationship between neuroplasticity (ability of the brain to change structurally and functionally), burn injury in older adults and rehabilitation outcomes. This thesis showed that non-injured older adults demonstrated a delayed repetitive transcranial magnetic stimulation (rTMS) induced neuroplastic response, whereas older adults with a minor burn injury demonstrated no rTMS-induced neuroplastic response at six weeks post-injury. Capacity for neuroplastic response may translate to better functional outcomes.

Original language	English
Qualification	Masters
Awarding Institution	The University of Western Australia
Supervisors/Advisors	Rea, Suzanne, Supervisor Edgar, Dale, Supervisor Wood, Fiona, Supervisor
Thesis sponsors	Australian Government Research Training Program
Award date	24 Oct 2018
DOIs	https://doi.org/10.26182/5bee643a233ba
Publication status	Unpublished - 2018

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10.26182/5bee643a233ba

THESIS - MASTER BY RESEARCH - WHIFE Casey John - 2018
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Cite this

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abstract = "Burn injury impacts physical function and quality of life in burns survivors beyond the initial injury. Deterioration in physical function post-burn injury becomes more apparent from approximately 45-50 years of age. This thesis investigated the relationship between neuroplasticity (ability of the brain to change structurally and functionally), burn injury in older adults and rehabilitation outcomes. This thesis showed that non-injured older adults demonstrated a delayed repetitive transcranial magnetic stimulation (rTMS) induced neuroplastic response, whereas older adults with a minor burn injury demonstrated no rTMS-induced neuroplastic response at six weeks post-injury. Capacity for neuroplastic response may translate to better functional outcomes.",

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KW - Theta burst stimulation

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KW - Short interval intracortical inhibition

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Investigating neuroplasticity in burn injury in older adults

Abstract

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