Average diagnostic age of Autism Spectrum Disorder (ASD) in Australia is 4.5 years. The overarching objective of this thesis vas to investigate potential prenatal and early postnatal markers of ASD risk. A prospective cohort of siblings of children with ASD ('high-risk' group) and siblings of typically developing children with no family history of ASD (low-risk' group) were recruited and assessed longitudinally from prenatal development up to age two. Data presented in this thesis indicate that differences between high-risk and low-risk siblings can be detected from as early as 6-months old and, from 12-months old, are predictive of later ASD classification.
|Qualification||Doctor of Philosophy|
|Award date||29 Mar 2017|
|Publication status||Unpublished - 2016|