Intravascular Tumor Extension and Pulmonary Tumor Embolism in Children With Solid Malignancies: Is There a Role for Inferior Vena Cava Filters?

Sarah M. Trinder, Sandra D. Ruhayel, Nicholas G. Gottardo, Clare A. McLaren, Anne L. Ryan, Derek J. Roebuck

Research output: Contribution to journalArticlepeer-review


Intravascular tumor extension is an uncommon complication of solid malignancies that, when present in the inferior vena cava (IVC), can result in fatal pulmonary tumor embolism. Currently, neoadjuvant chemotherapy and surgery are the mainstays of treatment; however, there are no consensus guidelines for management. We describe three cases of pediatric solid malignancies with associated IVC extension and pulmonary tumor embolism. We hypothesize that there is scope for IVC filter placement in such cases to mitigate the risk of fatal pulmonary tumor embolism.

Original languageEnglish
Pages (from-to)467-471
Number of pages5
JournalJournal of Pediatric Hematology/Oncology
Issue number8
Publication statusPublished - 1 Nov 2023

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