Intrapleural therapy for pleural infection from bronchopleural fistula in an adult with hyper-IgE syndrome

Sam Faber, Andrew McLean-Tooke, Yi Jin Kuok, Y. C.Gary Lee

Research output: Contribution to journalArticlepeer-review

Abstract

We presented the case of an adult patient with hyper-IgE syndrome (HIES) who was admitted acutely with a large hydropneumothorax from lung consolidation, a bronchopleural fistula and pleural infection. He has had recurrent pulmonary and skin infections since childhood and longstanding pneumatoceles. He was treated with systemic antibiotics and chest tube drainage. Administration of two doses of low-dose intrapleural therapy (1 mg tissue plasminogen activator and 5 mg deoxyribonuclease) allowed complete evacuation of his residual loculated pleural fluid, aided resolution of his infection without provoking a significant air leak and avoided the need for surgery.

Original languageEnglish
Article numbere01156
JournalRespirology Case Reports
Volume11
Issue number6
DOIs
Publication statusPublished - Jun 2023

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