© 2016 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of interventions with pregnant women and mothers of infants up to the age of 12 months on dental caries experience in their children up to the age of 6 years. Specifically, the intervention types include: 1) clinical interventions, 2) oral health education and promotion, and 3) policy and access to services.