Interference in radioimmunoassay of total serum thyroxin and free thyroxin due to thyroxin-binding autoantibodies

C. I. Bhagat; P. Garcia Webb; F. Watson; J. P. Beilby

doi:10.1093/clinchem/29.6.1324

Interference in radioimmunoassay of total serum thyroxin and free thyroxin due to thyroxin-binding autoantibodies

C. I. Bhagat, P. Garcia Webb, F. Watson, J. P. Beilby

Research output: Contribution to journal › Letter › peer-review

14 Citations (Scopus)

Abstract

The presence of a T₄-binding autoantibody resulted in a falsely high value for free T₄ and a falsely low one for total T₄ in a patient who was clinically euthyroid. Values for serum T₃ and thyrotropin were normal. Such results should alert the analyst to the possibility that the patient's serum contains autoantibodies.

Original language	English
Pages (from-to)	1324-1325
Number of pages	2
Journal	Clinical Chemistry
Volume	29
Issue number	6
DOIs	https://doi.org/10.1093/clinchem/29.6.1324
Publication status	Published - 1983
Externally published	Yes

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10.1093/clinchem/29.6.1324

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title = "Interference in radioimmunoassay of total serum thyroxin and free thyroxin due to thyroxin-binding autoantibodies",

abstract = "The presence of a T4-binding autoantibody resulted in a falsely high value for free T4 and a falsely low one for total T4 in a patient who was clinically euthyroid. Values for serum T3 and thyrotropin were normal. Such results should alert the analyst to the possibility that the patient's serum contains autoantibodies.",

author = "Bhagat, {C. I.} and {Garcia Webb}, P. and F. Watson and Beilby, {J. P.}",

year = "1983",

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AU - Bhagat, C. I.

AU - Garcia Webb, P.

AU - Watson, F.

AU - Beilby, J. P.

PY - 1983

Y1 - 1983

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AB - The presence of a T4-binding autoantibody resulted in a falsely high value for free T4 and a falsely low one for total T4 in a patient who was clinically euthyroid. Values for serum T3 and thyrotropin were normal. Such results should alert the analyst to the possibility that the patient's serum contains autoantibodies.

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U2 - 10.1093/clinchem/29.6.1324

DO - 10.1093/clinchem/29.6.1324

M3 - Letter

C2 - 6406097

AN - SCOPUS:0020967157

VL - 29

SP - 1324

EP - 1325

JO - Clinical Chemistry

JF - Clinical Chemistry

SN - 0009-9147

IS - 6

ER -

Interference in radioimmunoassay of total serum thyroxin and free thyroxin due to thyroxin-binding autoantibodies

Abstract

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