Insulin Pump Therapy is associated with Less Post-Exercise Hyperglycemia than multiple daily injections: An observational study of physically active type 1 diabetes patients

Background: Aerobic exercise typically decreases blood glucose levels in individuals with type 1 diabetes. It is currently unknown if glucose responses to exercise and recovery differ between patients on multiple daily insulin injections (MDI) and continuous subcutaneous insulin infusion (CSII). Subjects and Methods: Nineteen (16 male, three female) physically active individuals with type 1 diabetes took part in this observational study. Interstitial glucose levels (blinded) were compared during 45 min of standardized aerobic exercise (cycling or running at 60% peak aerobic capacity) and during 6 h of postexercise recovery between individuals using MDI (n=9) and CSII (n=10) therapy. Results: Both MDI and CSII groups had similar reductions in glucose levels during exercise, but responses in early and late recovery differed (group×time interaction, P12 mmol/L) compared with only 1/10th of the CSII patients (P