Inhibition of the exo-β-D-glucosaminidase CsxA by a glucosamine-configured castanospermine and an amino-australine analogue

B. Pluvinage; M.G. Ghinet; R. Brzezinski; A.B. Boraston; Keith Stubbs

doi:10.1039/b913235j

Inhibition of the exo-β-D-glucosaminidase CsxA by a glucosamine-configured castanospermine and an amino-australine analogue

B. Pluvinage, M.G. Ghinet, R. Brzezinski, A.B. Boraston, Keith Stubbs

School of Molecular Sciences

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

The synthesis of amino-derivatives of castanospermine and australine and their characterisation as inhibitors of the exo-β-D-glucosaminidase CsxA through enzyme kinetics and X-ray structural analysis is described.

Original language	English
Pages (from-to)	4169-4172
Journal	Organic & Biomolecular Chemistry
Volume	7
Issue number	20
DOIs	https://doi.org/10.1039/b913235j
Publication status	Published - 2009

Access to Document

10.1039/b913235j

Cite this

@article{f91a4ab1bf9c472284e7b7353bf0326a,

title = "Inhibition of the exo-β-D-glucosaminidase CsxA by a glucosamine-configured castanospermine and an amino-australine analogue",

abstract = "The synthesis of amino-derivatives of castanospermine and australine and their characterisation as inhibitors of the exo-β-D-glucosaminidase CsxA through enzyme kinetics and X-ray structural analysis is described.",

author = "B. Pluvinage and M.G. Ghinet and R. Brzezinski and A.B. Boraston and Keith Stubbs",

year = "2009",

doi = "10.1039/b913235j",

language = "English",

volume = "7",

pages = "4169--4172",

journal = "Organic & Biomolecular Chemistry",

issn = "1477-0520",

publisher = "The Royal Society of Chemistry",

number = "20",

}

TY - JOUR

T1 - Inhibition of the exo-β-D-glucosaminidase CsxA by a glucosamine-configured castanospermine and an amino-australine analogue

AU - Pluvinage, B.

AU - Ghinet, M.G.

AU - Brzezinski, R.

AU - Boraston, A.B.

AU - Stubbs, Keith

PY - 2009

Y1 - 2009

N2 - The synthesis of amino-derivatives of castanospermine and australine and their characterisation as inhibitors of the exo-β-D-glucosaminidase CsxA through enzyme kinetics and X-ray structural analysis is described.

AB - The synthesis of amino-derivatives of castanospermine and australine and their characterisation as inhibitors of the exo-β-D-glucosaminidase CsxA through enzyme kinetics and X-ray structural analysis is described.

U2 - 10.1039/b913235j

DO - 10.1039/b913235j

M3 - Article

C2 - 19795054

SN - 1477-0520

VL - 7

SP - 4169

EP - 4172

JO - Organic & Biomolecular Chemistry

JF - Organic & Biomolecular Chemistry

IS - 20

ER -

Inhibition of the exo-β-D-glucosaminidase CsxA by a glucosamine-configured castanospermine and an amino-australine analogue

Abstract

Access to Document

Fingerprint

Cite this