Fourteen antipsychotics of 5 different chemical classes were tested for their effects on mitochondrial succinate oxidation. Each of the compounds tested, with the exception of haloperidol, phenothiazine and prochlorperazine, inhibited succinate oxidation. The apparent inhibition constant for phenothiazine derivatives declined with increasing values of the partition coefficient.
|Number of pages||3|
|Journal||Veterinary and human toxicology: an official of journal of the American academy of veterinary and comparative toxicology|
|Publication status||Published - 1 Aug 2000|