Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720)

Tony Scalzo; S. Elliott; J. Cox; J. Gardner; D.J. Moss; A. Suhrbier

Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720)

Tony Scalzo, S. Elliott, J. Cox, J. Gardner, D.J. Moss, A. Suhrbier

Centre for Ophthalmology and Visual Science

Research output: Contribution to journal › Article

58 Citations (Scopus)

Abstract

The use of synthetic peptides representing cytotoxic T-cell (CTL) epitopes for human vaccination requires the identification of a suitable adjuvant formulation. A single immunization,vith Montanide ISA720/tetanus toxoid/YPHFMPTNL protected mice against murine cytomegalovirus and induced epitope-specific CTL. Such formulations will find application in peptide-based CTL anti-viral vaccines.

Original language	English
Pages (from-to)	1306-1309
Journal	Journal of Virology
Volume	69
Publication status	Published - 1995

Fingerprint Dive into the research topics of 'Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720)'. Together they form a unique fingerprint.

Cite this

@article{866ef1321b744ab791e13bc6e68cc9c7,

title = "Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720)",

abstract = "The use of synthetic peptides representing cytotoxic T-cell (CTL) epitopes for human vaccination requires the identification of a suitable adjuvant formulation. A single immunization,vith Montanide ISA720/tetanus toxoid/YPHFMPTNL protected mice against murine cytomegalovirus and induced epitope-specific CTL. Such formulations will find application in peptide-based CTL anti-viral vaccines.",

author = "Tony Scalzo and S. Elliott and J. Cox and J. Gardner and D.J. Moss and A. Suhrbier",

year = "1995",

language = "English",

volume = "69",

pages = "1306--1309",

journal = "Journal of Virology",

issn = "0022-538X",

publisher = "American Society for Microbiology",

}

TY - JOUR

T1 - Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720)

AU - Scalzo, Tony

AU - Elliott, S.

AU - Cox, J.

AU - Gardner, J.

AU - Moss, D.J.

AU - Suhrbier, A.

PY - 1995

Y1 - 1995

N2 - The use of synthetic peptides representing cytotoxic T-cell (CTL) epitopes for human vaccination requires the identification of a suitable adjuvant formulation. A single immunization,vith Montanide ISA720/tetanus toxoid/YPHFMPTNL protected mice against murine cytomegalovirus and induced epitope-specific CTL. Such formulations will find application in peptide-based CTL anti-viral vaccines.

AB - The use of synthetic peptides representing cytotoxic T-cell (CTL) epitopes for human vaccination requires the identification of a suitable adjuvant formulation. A single immunization,vith Montanide ISA720/tetanus toxoid/YPHFMPTNL protected mice against murine cytomegalovirus and induced epitope-specific CTL. Such formulations will find application in peptide-based CTL anti-viral vaccines.

M3 - Article

VL - 69

SP - 1306

EP - 1309

JO - Journal of Virology

JF - Journal of Virology

SN - 0022-538X

ER -