Individual variation in 3-methylbutanal: A putative link between human leukocyte antigen and skin microflora

S.U. Savelev; S. Antony-Babu; S.C. Roberts; H. Wang; A.S. Clare; L.M. Gosling; M. Petrie; M. Goodfellow; A.G. O'Donnell; A.C. Ward

doi:10.1007/s10886-008-9524-1

Individual variation in 3-methylbutanal: A putative link between human leukocyte antigen and skin microflora

S.U. Savelev, S. Antony-Babu, S.C. Roberts, H. Wang, A.S. Clare, L.M. Gosling, M. Petrie, M. Goodfellow, A.G. O'Donnell, A.C. Ward

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

The human derma emits volatile compounds whose interaction with a receiver’s olfactory sensory system may affect individual recognition and mating preferences. Studies suggest that both genes and environmental factors determine characteristic odor of an individual. We used solid-phase microextraction and gas chromatography–mass spectrometry to identify 3-methylbutanal in human axillary odor; we showed that the abundance of this volatile compound varies significantly among individuals and demonstrated that its formation in vitro may be influenced by interaction between human leukocyte antigen peptide and dermal microflora.

Original language	English
Pages (from-to)	1253-1257
Journal	Journal of Chemical Ecology
Volume	34
Issue number	9
DOIs	https://doi.org/10.1007/s10886-008-9524-1
Publication status	Published - 2008

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title = "Individual variation in 3-methylbutanal: A putative link between human leukocyte antigen and skin microflora",

abstract = "The human derma emits volatile compounds whose interaction with a receiver{\textquoteright}s olfactory sensory system may affect individual recognition and mating preferences. Studies suggest that both genes and environmental factors determine characteristic odor of an individual. We used solid-phase microextraction and gas chromatography–mass spectrometry to identify 3-methylbutanal in human axillary odor; we showed that the abundance of this volatile compound varies significantly among individuals and demonstrated that its formation in vitro may be influenced by interaction between human leukocyte antigen peptide and dermal microflora.",

author = "S.U. Savelev and S. Antony-Babu and S.C. Roberts and H. Wang and A.S. Clare and L.M. Gosling and M. Petrie and M. Goodfellow and A.G. O'Donnell and A.C. Ward",

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T1 - Individual variation in 3-methylbutanal: A putative link between human leukocyte antigen and skin microflora

AU - Savelev, S.U.

AU - Antony-Babu, S.

AU - Roberts, S.C.

AU - Wang, H.

AU - Clare, A.S.

AU - Gosling, L.M.

AU - Petrie, M.

AU - Goodfellow, M.

AU - O'Donnell, A.G.

AU - Ward, A.C.

PY - 2008

Y1 - 2008

N2 - The human derma emits volatile compounds whose interaction with a receiver’s olfactory sensory system may affect individual recognition and mating preferences. Studies suggest that both genes and environmental factors determine characteristic odor of an individual. We used solid-phase microextraction and gas chromatography–mass spectrometry to identify 3-methylbutanal in human axillary odor; we showed that the abundance of this volatile compound varies significantly among individuals and demonstrated that its formation in vitro may be influenced by interaction between human leukocyte antigen peptide and dermal microflora.

AB - The human derma emits volatile compounds whose interaction with a receiver’s olfactory sensory system may affect individual recognition and mating preferences. Studies suggest that both genes and environmental factors determine characteristic odor of an individual. We used solid-phase microextraction and gas chromatography–mass spectrometry to identify 3-methylbutanal in human axillary odor; we showed that the abundance of this volatile compound varies significantly among individuals and demonstrated that its formation in vitro may be influenced by interaction between human leukocyte antigen peptide and dermal microflora.

U2 - 10.1007/s10886-008-9524-1

DO - 10.1007/s10886-008-9524-1

M3 - Article

C2 - 18668292

SN - 0098-0331

VL - 34

SP - 1253

EP - 1257

JO - Journal of Chemical Ecology

JF - Journal of Chemical Ecology

IS - 9

ER -

Individual variation in 3-methylbutanal: A putative link between human leukocyte antigen and skin microflora

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