Abstract
The global obesity epidemic that now affects many countries in the world has
not improved in spite of dietary restriction, anti-obese foods and increased physical activity. The neuroendocrine system in many obese individuals is defective with an adipose tissue-liver defect that induces NAFLD and cardiovascular disease. Appetite control to reverse NAFLD and obesity has not been successful with revision of dietary composition that may allow activation of the adipose tissue-liver interaction. Indian spices are important to the adipose-tissue interaction but Indian spice intake should
be carefully controlled to avoid curcumin toxicity (apelin-Sirt 1 inhibition) associated with defective fat and caffeine metabolism and associated with the induction of autoimmune and neuroendocrine disease.
not improved in spite of dietary restriction, anti-obese foods and increased physical activity. The neuroendocrine system in many obese individuals is defective with an adipose tissue-liver defect that induces NAFLD and cardiovascular disease. Appetite control to reverse NAFLD and obesity has not been successful with revision of dietary composition that may allow activation of the adipose tissue-liver interaction. Indian spices are important to the adipose-tissue interaction but Indian spice intake should
be carefully controlled to avoid curcumin toxicity (apelin-Sirt 1 inhibition) associated with defective fat and caffeine metabolism and associated with the induction of autoimmune and neuroendocrine disease.
| Original language | English |
|---|---|
| Pages | 1-5 |
| Number of pages | 5 |
| Volume | 2 |
| Specialist publication | Annlas of Clinical Endocrinology and Metabolism |
| Publication status | Published - 1 Dec 2018 |
