Increasing Prevalence of Toxin A-Negative, Toxin B-Positive Isolates of Clostridium difficile in Korea: Impact on Laboratory Diagnosis

H. Kim, M. Kim, David Yong, Y. Chong, Thomas Riley, C.K. Kim, K. Lee, J-W. Park, Jae Park

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Of 462 Korean Clostridium difficile isolates, 77.5% were toxin B positive but 21.4% were toxin A negative (A– B+). The binary toxin gene was detected in nine isolates. A higher fluoroquinolone resistance of A– B+ strains may contribute to the increase of these strains. Toxin A detection alone may underdiagnose C. difficile-associated disease.
Original languageEnglish
Pages (from-to)1116-1117
JournalJournal of Clinical Microbiology
Volume46
Issue number3
DOIs
Publication statusPublished - 2008

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