Increased risk for obesity and diabetes with neurodegeneration in developing countries

Developing countries have come to the forefront because of the higher diabetes epidemic. The urbanization may possibly provide an explanation for the global diabetic epidemic. In Western countries the metabolic syndrome and non alcoholic fatty liver disease (NAFLD) has reached 30% of the population. In developing countries access to high calorie diets in urban areas promote NAFLD and interrupt the metabolism of xenobiotics that become toxic to various tissues such as the pancreas, heart, liver, kidney and the brain. Prevention programs are an important goal of international health organizations and in developing countries the plan to adapt a healthy diet, active lifestyle and reduced exposure to xenobiotics are important to manage the epidemic for obesity, diabetes and neurodegeneration in the developing and developed countries.