Inadvertent intrathecal use of ionic contrast agent

H. van der Leede, P. G. Jorens, P. Parizel, P. Cras

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Intrathecal administration of ionic contrast media may cause severe and fatal neurotoxic reactions due to their hyperosmolarity and ionic nature. They are therefore strictly contraindicated for all radiologic applications involving the central nervous system (e. g., myelography). We present a case in which ioxitalamate was accidentally injected intrathecally. The patient recovered completely due to a combination of the different therapeutic options reported in the literature, including early mechanical ventilation and neuromuscular paralysis, aggressive control of seizures, elevation of head and trunk to prevent cephalad migration of contrast, steroids, cerebrospinal fluid drainage and lavage and prophylactic antibiotics.

Original languageEnglish
Pages (from-to)S86-S93
Number of pages8
JournalEuropean Radiology
Publication statusPublished - Dec 2002
Externally publishedYes


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