In vivo terahertz reflection imaging of human scars during and after the healing process

Shuting Fan, Benjamin S Y Ung, Edward P J Parrott, Vincent P. Wallace, Emma Pickwell-Macpherson

    Research output: Contribution to journalArticle

    12 Citations (Scopus)

    Abstract

    We use terahertz imaging to measure four human skin scars in vivo. Clear contrast between the refractive index of the scar and surrounding tissue was observed for all of the scars, despite some being difficult to see with the naked eye. Additionally, we monitored the healing process of a hypertrophic scar. We found that the contrast in the absorption coefficient became less prominent after a few months post-injury, but that the contrast in the refractive index was still significant even months post-injury. Our results demonstrate the capability of terahertz imaging to quantitatively measure subtle changes in skin properties and this may be useful for improving scar treatment and management.
    Original languageEnglish
    Pages (from-to)1143-1151
    Number of pages9
    JournalJournal of Biophotonics
    Volume10
    Issue number9
    DOIs
    Publication statusPublished - Sep 2017

    Fingerprint

    Terahertz Imaging
    scars
    healing
    Cicatrix
    Refractive index
    Skin
    Imaging techniques
    Refractometry
    Tissue
    Hypertrophic Cicatrix
    refractivity
    Wounds and Injuries
    absorptivity

    Cite this

    Fan, Shuting ; Ung, Benjamin S Y ; Parrott, Edward P J ; Wallace, Vincent P. ; Pickwell-Macpherson, Emma. / In vivo terahertz reflection imaging of human scars during and after the healing process. In: Journal of Biophotonics. 2017 ; Vol. 10, No. 9. pp. 1143-1151.
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    abstract = "We use terahertz imaging to measure four human skin scars in vivo. Clear contrast between the refractive index of the scar and surrounding tissue was observed for all of the scars, despite some being difficult to see with the naked eye. Additionally, we monitored the healing process of a hypertrophic scar. We found that the contrast in the absorption coefficient became less prominent after a few months post-injury, but that the contrast in the refractive index was still significant even months post-injury. Our results demonstrate the capability of terahertz imaging to quantitatively measure subtle changes in skin properties and this may be useful for improving scar treatment and management.",
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    In vivo terahertz reflection imaging of human scars during and after the healing process. / Fan, Shuting; Ung, Benjamin S Y; Parrott, Edward P J; Wallace, Vincent P.; Pickwell-Macpherson, Emma.

    In: Journal of Biophotonics, Vol. 10, No. 9, 09.2017, p. 1143-1151.

    Research output: Contribution to journalArticle

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