@inbook{5d01fdbebb6b4102b9aec10ad2b108a9,
title = "In Vitro 3D Mechanical Stimulation to Tendon-Derived Stem Cells by Bioreactor",
abstract = "Bioreactors can offer an advanced platform to provide conditions that mimic the native microenvironment, which can also provide stretching environment for mechanobiology research. Tendon-derived stem cells (TDSCs) are a type of mechanosensitive and multipotent cells, which behave differently in diverse mechanical stretching environments. We have proved the in vitro three-dimensional (3D) mechanical stimulation could closely mimic the stretching environment in vivo. Thus, here we describe applying a customized bioreactor to provide 3D force for mechanical stimulation on TDSC in vitro.",
keywords = "Bioreactor, Mechanical loading, Mechanobiology, RT-qPCR, Tendon formation",
author = "Ziming Chen and Peilin Chen and Rui Ruan and Minghao Zheng",
note = "Funding Information: The authors acknowledge financial support from Australian Research Council Industrial Transformation Training Centre for Personalised Therapeutics Technologies (IC170100016). Publisher Copyright: {\textcopyright} 2021, Springer Science+Business Media, LLC.",
year = "2022",
doi = "10.1007/7651_2021_432",
language = "English",
isbn = "978-1-0716-2017-5",
series = "Methods in Molecular Biology",
publisher = "Humana Press",
pages = "135--144",
editor = "Turksen, {Kursad }",
booktitle = "Bioreactors in Stem Cell Biology",
address = "United States",
edition = "2nd",
}