Improvements to the Synthesis of Isofagomine, Noeuromycin, Azafagomine, and Isofagomine Lactam, and a Synthesis of Azanoeuromycin and 'Guanidine' Isofagomine

P.J. Meloncelli, Robert Stick

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Improvements in the preparation of a key imidazylate and the reduction of the derived nitrile have led to more efficient syntheses of isofagomine, noeuromycin, azafagomine, and isofagomine lactam. As well, a precursor of azafagomine has been converted into azanoeuromycin, and the nitrogen atom of isofagomine has been incorporated into a guanidine residue.
Original languageEnglish
Pages (from-to)827-833
JournalAustralian Journal of Chemistry: an international journal for chemical science
Volume59
Issue number11
DOIs
Publication statusPublished - 2006

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