Abstract
Acute gastroenteritis is a leading cause of global morbidity. Rotavirus is the most common cause of severe gastroenteritis, especially in young children. Using record-linked health administrative data, this thesis describes the impact of rotavirus vaccination on the epidemiology of gastroenteritis (including rotavirus) in Western Australia.
Findings from this thesis demonstrate the safety and effectiveness of rotavirus vaccination in preventing gastroenteritis. It also identifies the population subgroups with increased risk of severe gastroenteritis and suboptimal rotavirus vaccination uptake. Given the beneficial effects of rotavirus vaccination, efforts should be taken to optimise rotavirus vaccine coverage in those at highest risk.
Findings from this thesis demonstrate the safety and effectiveness of rotavirus vaccination in preventing gastroenteritis. It also identifies the population subgroups with increased risk of severe gastroenteritis and suboptimal rotavirus vaccination uptake. Given the beneficial effects of rotavirus vaccination, efforts should be taken to optimise rotavirus vaccine coverage in those at highest risk.
Original language | English |
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Qualification | Doctor of Philosophy |
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Award date | 10 Jun 2020 |
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Publication status | Unpublished - 2020 |