Impact of rotavirus vaccination in Western Australia

Parveen Fathima

doi:10.26182/5f166a642b2d4

Impact of rotavirus vaccination in Western Australia

Parveen Fathima

UWA Medical School

Research output: Thesis › Doctoral Thesis

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Abstract

Acute gastroenteritis is a leading cause of global morbidity. Rotavirus is the most common cause of severe gastroenteritis, especially in young children. Using record-linked health administrative data, this thesis describes the impact of rotavirus vaccination on the epidemiology of gastroenteritis (including rotavirus) in Western Australia.
Findings from this thesis demonstrate the safety and effectiveness of rotavirus vaccination in preventing gastroenteritis. It also identifies the population subgroups with increased risk of severe gastroenteritis and suboptimal rotavirus vaccination uptake. Given the beneficial effects of rotavirus vaccination, efforts should be taken to optimise rotavirus vaccine coverage in those at highest risk.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	The University of Western Australia
Supervisors/Advisors	Moore, Hannah, Supervisor Blyth, Christopher, Supervisor Gibbs, Robyn A., Supervisor, External person Effler, Paul, Supervisor
Thesis sponsors	Australian Government Research Training Program
Award date	10 Jun 2020
DOIs	https://doi.org/10.26182/5f166a642b2d4
Publication status	Unpublished - 2020

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10.26182/5f166a642b2d4

TH20 153 THESIS - DOCTOR OF PHILOSOPHY - FATHIMA Parveen - 2020
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Cite this

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title = "Impact of rotavirus vaccination in Western Australia",

abstract = "Acute gastroenteritis is a leading cause of global morbidity. Rotavirus is the most common cause of severe gastroenteritis, especially in young children. Using record-linked health administrative data, this thesis describes the impact of rotavirus vaccination on the epidemiology of gastroenteritis (including rotavirus) in Western Australia. Findings from this thesis demonstrate the safety and effectiveness of rotavirus vaccination in preventing gastroenteritis. It also identifies the population subgroups with increased risk of severe gastroenteritis and suboptimal rotavirus vaccination uptake. Given the beneficial effects of rotavirus vaccination, efforts should be taken to optimise rotavirus vaccine coverage in those at highest risk. ",

keywords = "Rotavirus, Vaccine safety, Gastroenteritis, Record-linkage, Rotavirus vaccine, Epidemiology, Vaccine effectiveness",

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language = "English",

school = "The University of Western Australia",

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AB - Acute gastroenteritis is a leading cause of global morbidity. Rotavirus is the most common cause of severe gastroenteritis, especially in young children. Using record-linked health administrative data, this thesis describes the impact of rotavirus vaccination on the epidemiology of gastroenteritis (including rotavirus) in Western Australia. Findings from this thesis demonstrate the safety and effectiveness of rotavirus vaccination in preventing gastroenteritis. It also identifies the population subgroups with increased risk of severe gastroenteritis and suboptimal rotavirus vaccination uptake. Given the beneficial effects of rotavirus vaccination, efforts should be taken to optimise rotavirus vaccine coverage in those at highest risk.

KW - Rotavirus

KW - Vaccine safety

KW - Gastroenteritis

KW - Record-linkage

KW - Rotavirus vaccine

KW - Epidemiology

KW - Vaccine effectiveness

U2 - 10.26182/5f166a642b2d4

DO - 10.26182/5f166a642b2d4

M3 - Doctoral Thesis

ER -

Impact of rotavirus vaccination in Western Australia

Abstract

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