Immuno-nephelometric determination of group streptococcal anti-streptolysin O titres (ASOT) from dried blood spots: Method for validating a new assay

John Joseph, Neil Kent, Asha Bowen, Julie Hart, Meru Sheel, Robert Wardrop, Sam Abbs, Scott Bazely, Monika Rybak

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Abstract

This study was designed to determine the sensitivity and reproducibility of recovering anti-streptolysin O titres (ASOT) from dried blood spot (DBS) samples, a methodologic subcomponent of the penicillin pharmacokinetic studies in children receiving secondary prophylaxis with intramuscular benzathine penicillin for acute rheumatic fever.

Original languageEnglish
Pages (from-to)59-65
Number of pages7
JournalJournal of Immunological Methods
Volume448
DOIs
Publication statusPublished - 1 Sep 2017

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