Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Luke R. Holmes; Rishi S. Kotecha; Derek J. Roebuck

doi:10.1111/1754-9485.13852

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Paediatrics

Research output: Contribution to journal › Review article › peer-review

Abstract

Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer-related death in children and adolescents. Five-year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the mortality from treatment-related toxicity approaching rates that are associated with relapse. This manuscript reviews the imaging features of the common treatment-associated abdominal complications in children with ALL.

Original language	English
Number of pages	12
Journal	Journal of Medical Imaging and Radiation Oncology
DOIs	https://doi.org/10.1111/1754-9485.13852
Publication status	E-pub ahead of print - 27 Mar 2025

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10.1111/1754-9485.13852Licence: CC BY-NC-ND

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title = "Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia",

abstract = "Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer-related death in children and adolescents. Five-year overall survival rates now exceed 90\% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the mortality from treatment-related toxicity approaching rates that are associated with relapse. This manuscript reviews the imaging features of the common treatment-associated abdominal complications in children with ALL.",

keywords = "Acute lymphoblastic leukaemia, Complications, Diagnostic imaging, Paediatrics, Pancreatitis",

author = "Holmes, \{Luke R.\} and Kotecha, \{Rishi S.\} and Roebuck, \{Derek J.\}",

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doi = "10.1111/1754-9485.13852",

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AU - Holmes, Luke R.

AU - Kotecha, Rishi S.

AU - Roebuck, Derek J.

PY - 2025/3/27

Y1 - 2025/3/27

N2 - Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer-related death in children and adolescents. Five-year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the mortality from treatment-related toxicity approaching rates that are associated with relapse. This manuscript reviews the imaging features of the common treatment-associated abdominal complications in children with ALL.

AB - Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer-related death in children and adolescents. Five-year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the mortality from treatment-related toxicity approaching rates that are associated with relapse. This manuscript reviews the imaging features of the common treatment-associated abdominal complications in children with ALL.

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KW - Complications

KW - Diagnostic imaging

KW - Paediatrics

KW - Pancreatitis

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JO - Journal of Medical Imaging and Radiation Oncology

JF - Journal of Medical Imaging and Radiation Oncology

ER -

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Abstract

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