Identification of new flaviviruses in the Kokobera virus complex

D.J. Nisbet, K.J. Lee, A.F. Van Den Hurk, Cheryl Johansen, G. Kuno, G-J.J. Chang, J.S. Mackenzie, S.A. Ritchie, R.A. Hall

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24 Citations (Scopus)

Abstract

Novel flavivirus isolates from mosquitoes collected in northern Australia were analysed by partial genomic sequencing, monoclonal antibody-binding assays and polyclonal cross-neutralization tests. Two isolates were found to be antigenically distinct from, but related to, viruses of the Kokobera virus complex, which currently contains Kokobera (KOKV) and Stratford (STRV) viruses. Nucleotide sequence comparison of two separate regions of the genome revealed that an isolate from Saibai Island in the Torres Strait in 2000 (TS5273) was related closely to KOKV and STRV, with 74-80 and 75-76% nucleotide similarity, respectively. An isolate from mainland Cape York in 1998 (CY1014) was found to be more divergent from KOKV and STRV, with
Original languageEnglish
Pages (from-to)121-124
JournalJournal of General Virology
Volume86
DOIs
Publication statusPublished - 2005

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    Nisbet, D. J., Lee, K. J., Van Den Hurk, A. F., Johansen, C., Kuno, G., Chang, G-JJ., ... Hall, R. A. (2005). Identification of new flaviviruses in the Kokobera virus complex. Journal of General Virology, 86, 121-124. https://doi.org/10.1099/vir.0.80381-0