Identification of a novel HLA-A allele, HLA-A01:195, in a UAE national

W. Abdrabou, I.I. Witzel, A. Paduch, Guan Tay, H. Alsafar

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

© 2016 American Society for Histocompatibility and ImmunogeneticsA novel human leucocyte antigen (HLA)-A allele, HLA-A01:195, was identified by sequence-based typing (SBT) in a UAE national subject. The novel allele is identical to its closest known allele, HLA-A01:01:01:01, in exon 2, 3 and 4, except for a single nucleotide mutation of A to G at position 442 in exon 3 (codon 124 in the a2 domain of the a chain of the mature protein). This A to G mutation results in an amino acid change of isoleucine #124 to valine.
Original languageEnglish
Pages (from-to)605-608
JournalHuman Immunology
Volume77
Issue number7
DOIs
Publication statusPublished - 2016

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