Abstract
© 2016 American Society for Histocompatibility and ImmunogeneticsA novel human leucocyte antigen (HLA)-A allele, HLA-A01:195, was identified by sequence-based typing (SBT) in a UAE national subject. The novel allele is identical to its closest known allele, HLA-A01:01:01:01, in exon 2, 3 and 4, except for a single nucleotide mutation of A to G at position 442 in exon 3 (codon 124 in the a2 domain of the a chain of the mature protein). This A to G mutation results in an amino acid change of isoleucine #124 to valine.
Original language | English |
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Pages (from-to) | 605-608 |
Number of pages | 4 |
Journal | Human Immunology |
Volume | 77 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1 Jul 2016 |